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Found 527 clinical trials
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Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan

The aim of this study is to test a model of demographic (age, sex), clinical, cognitive, and neurocircuitry predictors of emotion regulation ability and long-term depressive symptoms.

depressive symptoms
depression
Accepts healthy volunteers
  • 140 views
  • 29 Nov, 2021
  • 2 locations
None
A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant

The purpose of this study is to assess the safety (adverse events, serious adverse events, deaths, suicidality) of participants with major depressive disorder (MDD) treated according to the

  • 0 views
  • 21 Nov, 2021
  • 5 locations
None
Sex Hormones and Gamma-Aminobutyric Acid (GABA) in Stress Induced Anhedonia in Depression

differences in Major Depressive Disorder (MDD). Further, the investigators will link these markers to symptoms of depression.

psychotropic drugs
psychiatric disorder
major depressive disorder
anxiety
depression
  • 90 views
  • 29 Jan, 2021
  • 1 location
None
Long-term Study With Trazodone Once-a-Day

The aim of the present observational study is to assess the clinical response, functional impairment and quality of life in outpatients with Major Depressive Disorder who demonstrated an initial

psychiatric disorder
major depressive disorder
  • 0 views
  • 30 Oct, 2021
  • 1 location
None
Tracking Response to Antidepressants in Advance of Investigational Trials

individuals meeting criteria for Major Depressive Disorder (MDD) and seeking enrollment in investigational trials.

  • 0 views
  • 19 Mar, 2021
  • 1 location
None
A Kynurenine Pathway-based Molecular Imaging Study of Individualized Diagnosis and Treatment for Major Depressive Disorder

Major depressive disorder (MDD) is a chronic disease with high incidence rate, high recurrent rate and need whole course medical management. Varied clinical symptoms and unclear pathogenesis

depressed mood
antidepressants
psychiatric disorder
major depressive disorder
selective serotonin reuptake inhibitors
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Clinical Validation of a Combinatorial PharmAcogeNomic Approach in Major Depressive Disorder: an Observational Prospective RAndomized Single-blind Controlled Trial

Major depressive disorder (MDD) is a common, chronic, debilitating mood disorder causing serious functional impairment and significantly decreased quality of life. Pharmacotherapy represents the

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression

The overarching goal of the present study is to evaluate the effect of a subanesthetic dose of ketamine 24-hour post-injection on resting state functional connectivity, cognitive control, and reward learning.

drugs of abuse
antidepressants
scid
structured clinical interview
psychosis
  • 0 views
  • 14 Aug, 2021
  • 1 location
None
Tracking Response to Antidepressants in Advance of Investigational Trials Relapse Study

TRAIT-RS is an observational study to evaluate ongoing treatment response stability to standard of care antidepressant treatments (ADTs) among individuals who met criteria for Major Depressive

  • 0 views
  • 01 Jul, 2021
  • 1 location
None
The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments

The study will apply state of the art radiology through advanced magnetic resonance imaging (MRI) techniques to investigate structural and functional brain effects of electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS).

Accepts healthy volunteers
  • 0 views
  • 30 Nov, 2021
  • 1 location