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Found 531 clinical trials
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Assessing an EEG Biomarker of Response to TMS for Major Depression

Veterans with treatment resistant depression (TRD) have the opportunity to receive transcranial magnetic stimulation (TMS) treatment via the VA's National TMS Clinical Pilot Program. While some see improvement with their depression, others do not. Therefore, it may be beneficial to be able to predict with biomarkers what participants may see …

transcranial magnetic stimulation
treatment resistant depression
psychotherapy
depressed mood
  • 0 views
  • 24 Sep, 2021
  • 1 location
None
University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD). These treatments include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), racemic ketamine infusion and intranasal esketamine insufflation. The investigators will obtain various indicators, or biomarkers, of a depressed individuals' state before, during, and/or …

antidepressants
bipolar disorder
depressed mood
esketamine
depressive episode
  • 0 views
  • 18 Apr, 2021
  • 1 location
None
Relationship About Pregnancy Health and Offspring Developmental &Behavioral Outcomes

This topic puts forward a hypothesis: genetic and environmental factors such as major depressive disorder during pregnancy, nutritional status of vitamin A, D, E, and folic acid, intestinal

major depressive disorder
folic acid
folate
  • 64 views
  • 05 Feb, 2021
  • 5 locations
None
Valved Graft PMCF Study

MDD. Device safety will be evaluated by comparing 5-year annualized rate of all-cause mortality in subjects implanted with an Abbott Valved Graft during aortic valve and ascending

  • 0 views
  • 11 Aug, 2021
  • 9 locations
None
Characterization and Treatment of Adolescent Depression

> People ages 11 17 with major depressive disorder or subthreshold depression Healthy volunteers ages 11 17 Design Participants will be screened with

suicide
suicidal
depressive disorder
major depressive disorder
insomnia
  • 85 views
  • 06 Aug, 2021
  • 1 location
None
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, …

brain imaging
suicide
psychiatric treatment
anxiety
bipolar disorder
  • 265 views
  • 05 Dec, 2021
  • 1 location
None
Outcomes Associated With Suicidality in Inpatients With Symptoms of Depression (OASIS-D)

This 6-month, naturalistic cohort study examines male and female inpatients aged 18 to 75 years i) with any form of unipolar depressive episode (cohort 1); ii) clinical diagnosis of a moderate or severe unipolar depressive episode and suicidal tendencies who agree to participate in a prospective study (cohort 2); and …

depressive symptoms
depressive episode
suicidal
depressive disorder
depression
  • 0 views
  • 27 May, 2021
  • 1 location
None
Family Study of Affective and Anxiety Spectrum Disorders

This study will examine how depression, anxiety, and migraine run in families. It will help in defining the risk factors for physical, mental, and health problems-as well as define ways that those problems may be prevented and treated. A broad range of ages among family members will be included to …

progesterone
family study
mania
anxiety
migraine
  • 716 views
  • 06 Nov, 2021
  • 1 location
None
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry

While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve the delivery of care and the quality of outcomes for youths, adults and seniors with depression across the Maritimes. The investigators …

depression
psychiatric disorder
depressed mood
  • 703 views
  • 23 Jan, 2021
  • 1 location
None
Intestinal Flora and Major Depressive Disorders

As an important micro-ecological factor in human body, intestinal flora is closely related to the occurrence and development of major depressive disorder. The purpose of our study is to

probe
duloxetine
body mass index
depression
major depressive disorder
  • 0 views
  • 24 Jan, 2021
  • 1 location