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Found 465 clinical trials
Intestinal Flora and Major Depressive Disorders (IFMDD)

As an important micro-ecological factor in human body, intestinal flora is closely related to the occurrence and development of major depressive disorder. The purpose of our study is to

remission
depression
probe
major depressive disorder
body mass index
  • 0 views
  • 05 Mar, 2022
  • 1 location
Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan

The aim of this study is to test a model of demographic (age, sex), clinical, cognitive, and neurocircuitry predictors of emotion regulation ability and long-term depressive symptoms.

depression
depressive symptoms
Accepts healthy volunteers
  • 323 views
  • 02 Dec, 2021
  • 2 locations
Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA (PROSPECT)

Prospective observational cohort study to determine cost-effectiveness of ECT compared to medication (TCA) in the treatment of major depressive disorder (MDD) in the Netherlands.

  • 0 views
  • 23 Apr, 2022
  • 2 locations
Personalized Escitalopram Dosing in Patients With Depression (PsyCise-E)

The aims of this study are to: Determine the proportion of participants who are underdosed or overdosed under recommended dosing regimen of escitalopram for the depression treatment (10 mg/day) Determine and quantify clinical benefits of personalized escitalopram dosing regimen based on the escitalopram blood level monitoring Retrospectively estimate whether the …

  • 0 views
  • 23 Mar, 2022
  • 2 locations
Personalized Sertraline Dosing in Patients With Depression (PsyCise-S)

The aims of this study are to: Determine the proportion of participants who are underdosed or overdosed under recommended dosing regimen of sertraline for the depression treatment (100 mg/day) Determine and quantify clinical benefits of personalized sertraline dosing regimen based on the sertraline blood level monitoring Retrospectively estimate whether the …

  • 0 views
  • 22 Mar, 2022
  • 2 locations
A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant

The purpose of this study is to assess the safety (adverse events, serious adverse events, deaths, suicidality) of participants with major depressive disorder (MDD) treated according to the

  • 0 views
  • 25 May, 2022
  • 3 locations
Tracking Response to Antidepressants in Advance of Investigational Trials

individuals meeting criteria for Major Depressive Disorder (MDD) and seeking enrollment in investigational trials.

  • 0 views
  • 19 Mar, 2021
  • 1 location
Clinical Validation of a Combinatorial PharmAcogeNomic Approach in Major Depressive Disorder: an Observational Prospective RAndomized Single-blind Controlled Trial

Major depressive disorder (MDD) is a common, chronic, debilitating mood disorder causing serious functional impairment and significantly decreased quality of life. Pharmacotherapy represents the

  • 0 views
  • 26 Jan, 2021
  • 1 location
Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression

The overarching goal of the present study is to evaluate the effect of a subanesthetic dose of ketamine 24-hour post-injection on resting state functional connectivity, cognitive control, and reward learning.

structured clinical interview
psychiatric disorder
drugs of abuse
antidepressants
ketamine
  • 40 views
  • 14 Aug, 2021
  • 1 location
Tracking Response to Antidepressants in Advance of Investigational Trials Relapse Study

TRAIT-RS is an observational study to evaluate ongoing treatment response stability to standard of care antidepressant treatments (ADTs) among individuals who met criteria for Major Depressive

  • 0 views
  • 01 Jul, 2021
  • 1 location