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Found 465 clinical trials
Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

The study aims to investigate the safety and efficacy of oral psilocybin administered under supportive conditions in treatment-resistant major depression (TRD). The study is a bi-centric

  • 0 views
  • 08 Aug, 2021
  • 2 locations
Efficacy Study of Deep Brain Stimulation in Patients With Treatment Resistant Major Depression (FORESEE III)

Stimulation (DBS) in patients with treatment resistant major depression using the Boston Scientific implantable Vercise GEVIA DBS system compared to sham.

  • 55 views
  • 14 Feb, 2022
  • 1 location
Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention (ENDURE)

This is a rater-blinded, randomized controlled trial. All patients will receive esketamine for treatment of Major Depression with Suicidal Ideation (MDSI). Subjects will be randomized (1:1) to

  • 0 views
  • 22 Jul, 2022
  • 2 locations
A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

The clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy. The objective

  • 362 views
  • 29 Jul, 2022
  • 27 locations
Optimal Dose of a Cognitive Control Training for Depression Vulnerability

This study aims to examine the dose-response relationship of an online adaptive cognitive control training on depressive symptomatology and rumination. Participants will be randomized over six groups, each receiving a different dose (0, 1, 5, 10, 15 or 20 sessions) of a cognitive control training in remitted depressed patients. An …

Accepts healthy volunteers
  • 0 views
  • 14 Apr, 2022
  • 1 location
Feasibility of Adherence to Light Therapy

In this feasibility study, we propose an important question: What factors will affect participant adherence to the daily use of light therapy for maintenance treatment of depression? To answer this question, we will conduct a pilot study of open-label treatment with light therapy in a small sample (n=10) of participants …

  • 0 views
  • 06 Oct, 2021
  • 1 location
The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Postpartum depression is a serious disorder that affects approximately 14% of women who have recently given birth. Postpartum depression is either an episode of major depressive disorder (only

depressed mood
antidepressants
quetiapine
depressive disorder
  • 0 views
  • 14 Apr, 2022
  • 1 location
Accelerated Intermittent Theta Burst Stimulation for Depressed Patients During the Covid-19 Pandemic

depressive disorder. An accelerated course is of particular interest given the safety profile of the procedure and the potential to treat people more quickly making the treatment more accessible. This study

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
Psilocybin in Depression Resistant to Standard Treatments

treatment resistant major depressive disorder. The primary objective is to evaluate feasibility by measuring recruitment rates, dropout rates and by estimating the variance of the primary outcome measure

  • 19 views
  • 30 Jul, 2021
  • 1 location
A Study in Healthy Japanese Men to Test How Well Different Doses of BI 1569912 Are Tolerated

basis for a clinical development of BI 1569912 in the indication for Major Depressive Disorder (MDD) in Japan.

  • 0 views
  • 21 Jul, 2022
  • 1 location