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Found 325 clinical trials
A Study to Learn About First-line Avelumab Maintenance in Japanese Patients With Locally Advanced or Metastatic Urothelial Carcinoma

metastatic urothelial carcinoma patients who were treated with avelumab as first-line maintenance therapy between 24 February 2021 and 30 November 2021 in Japan. Participants will take part in this study up

metastatic urothelial carcinoma
avelumab
  • 0 views
  • 07 Oct, 2022
  • 1 location
A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL

With the development of molecular biology and precise medical treatment, new challenges have been raised in the diagnosis and treatment of non-Hodgkin lymphoma (NHL) in children. In recent years, the criteria for clinical staging and efficacy evaluation of NHL in children have been updated. Recent clinical studies of COG in …

PTEN
lymphoblastic lymphoma
cancer
hodgkin's disease
  • 5 views
  • 30 May, 2022
  • 1 location
A Pan-European Non-interventional, Retrospective Observational Cohort Study of Patients With BRCA Mutated Advanced (FIGO Stage III-IV) Ovarian Cancer Treated With Olaparib Tablets in the First-line Maintenance Setting (OVAL-1)

This is a retrospective observational medical records review study of BRCA mutated advanced (FIGO stage III-IV) ovarian cancer patients who received first dose maintenance olaparib in 1L setting in France, Italy and the UK. Physicians who treated ovarian cancer patients with olaparib in 1L setting will be requested to recruit …

ovarian epithelial carcinoma
platinum-based chemotherapy
olaparib
cancer of the ovary
cancer chemotherapy
  • 0 views
  • 13 Oct, 2022
  • 1 location
A Prospective, Observational Study, to Evaluate the Maintenance With Bortezomib Plus Daratumumab (V-Dara) After Induction With Bortezomib, Melphalan, Prednisone Plus Daratumumab (VMP-Dara) in Newly Diagnosed Multiple Myeloma (MM) Patients Non-eligible for Autologous Stem Cell Transplantation (ASCT): Alcyone-optimized Real World Evidence (RWE) Data

This is a prospective, observational, single group and multicenter study to describe the effectiveness and safety of maintenance with V-Dara after induction with the VMP-Dara regimen in newly diagnosed MM patients who are not eligible for ASCT. Patients will be enrolled in the study during a regularly scheduled office visit …

prednisone
melphalan
bortezomib
  • 0 views
  • 12 Oct, 2022
  • 24 locations
Computational Psychiatric Approach for Prognosis of Medication-Resistant Depression

The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression. Subjects will be invited to be in this study because (1) they are a patient about to receive ECT treatment for depression, or (2) they are a patient diagnosed with …

Accepts healthy volunteers
depressed mood
depressive symptoms
  • 289 views
  • 28 Oct, 2022
  • 1 location
Bespoke ctDNA Assay for Recurrence and Treatment Response Monitoring in Advanced Epithelial Ovarian Cancer (EOC)

This prospective observational study is to assess the dynamics of circulating tumor DNA (ctDNA) in patients with advanced epithelial ovarian cancer (EOC) undergoing surgery , adjuvant chemotherapy, followed by poly adenosine diphosphate-ribose polymerase (PARP) inhibitors until disease progression or the end of the study. All patients will be closely monitored …

ovarian epithelial carcinoma
cancer antigen 125
cancer of the ovary
cytoreductive surgery
cancer chemotherapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Secondary Central Nervous System Lymphoma Registry - Charit

The objective of the observation is to collect and document data on treatment strategies for secondary central nervous system lymphoma (SCNSL) in routine clinical practice, whether obtained in the context of clinical trials or outside of trials. In particular, the following questions will be specified: What therapeutic approaches are being …

  • 0 views
  • 14 Nov, 2021
  • 1 location
Prospective Evaluation of Immunological Molecular-genetic Image-based and Microbial Analyzes to Characterize Tumor Response and Control in Patients With Inoperable Stage III NSCLC Treated With Chemoradiotherapy Followed by Consolidation Therapy With Durvalumab

This non-interventional single-center explorative biomarker study aims at longitudinal comprehensive characterization (molecular genetics, immunological, morphological, image-based and microbial features) of the patient (host) and tumor as well as changes during standard treatment and in case of recurrent disease in inoperable stage III non-small cell lung cancer (NSCLC). Comprehensive analysis will …

chemotherapy regimen
lung cancer
PET-CT
cancer
carcinoma
  • 0 views
  • 16 Sep, 2021
  • 1 location
VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma (VISION)

The 3-drug therapy of Bortezomib-Melphalan-Prednisolone (VMP) is a standard therapy that is commonly used currently in South Korea as a first-line treatment for treatment-nave patients with multiple myeloma who are ineligible for hematopoietic transplantation. Despite the fact that VMP therapy is outstanding in terms of cost-effectiveness, treatment discontinuation rates due …

melphalan
bortezomib
  • 1 views
  • 17 Feb, 2022
  • 20 locations
RWE of Pediatric-like Protocol for AYA Patients With Ph-negative ALL

This is a multicenter, observational real world clinical trial with prospective follow up that will evaluate the treatment outcome of adolescent and young patients with ph-negative acute lymphoblastic leukemia with first-line pediatric-like protocol in Argentina.

  • 0 views
  • 26 Nov, 2021
  • 1 location