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Found 15 clinical trials
Improving Care Through Azithromycin Research for Infants in Africa

will also assess the efficacy of adding a dose of IPTi-SP at this age. Recent studies show that azithromycin (AZi) - a macrolide antibiotic with some antimalarial effect- is associated with a

  • 0 views
  • 21 Sep, 2021
  • 1 location
Mortalite Infantile Reduite Par l'Administration de Masse de l'Azitromycine (MIRAMA)

This trial will investigate the supplementation of azithromycin distribution to the "Child Health Days" platform in Burkina Faso for child mortality reduction. This distribution will pair door-to-door administration of vitamin A and azithromycin or placebo with acute malnutrition screening among children 1-11 months old.

Accepts healthy volunteers
  • 0 views
  • 23 Oct, 2022
Community Health Azithromycin Trial in Burkina Faso (CHAT)

An estimated 7.7 million pre-school aged children die each year, the majority from infectious diseases. Mass azithromycin distributions for trachoma may have the unintended benefit of reducing childhood mortality. We recently demonstrated the biannual mass azithromycin distribution significantly reduces all-cause child mortality in a cluster randomized trial (MORDOR I) conducted …

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location
Treatment of ppROM With Erythromycin vs. Azithromycin Trial (TREAT)

a second-generation macrolide (azithromycin) instead of erythromycin. Azithromycin can be taken once daily, is cheaper than erythromycin and has less GI upset adverse effects. The investigators

  • 51 views
  • 04 Oct, 2022
  • 3 locations
Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY) (SY-DOXY)

treatment for one day to be effective against early syphilis, but most authors agree that azithromycin should not generally be used as resistance to this macrolide is highly prevalent in Western countries

  • 0 views
  • 26 Apr, 2022
  • 1 location
Efficacy of Azithromycin Plus Doxycycline Versus Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever (Rocky-Z)

The aim of this study is to impove the pharmacological treatment of Rocky mountain spotted fever, since is a very ancient disease with an antibiotic therapy that have not changed much the mortality rates, being compared with the natural curse of the disease.

  • 0 views
  • 19 Jun, 2022
  • 1 location
Incidence of Acute Laryngeal Injury Following Endotracheal Intubation

The purpose of this investigation is to delineate the incidence of acute and chronic laryngeal injury following intubation within our health system. In addition, this study seeks to identify risk factors for airway injury that may provide information to help reduce the incidence of injury or increase the speed of …

budesonide
endotracheal intubation
  • 138 views
  • 05 Nov, 2021
  • 1 location
Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)

NTM therapy consists of a multi-drug macrolide based regimen for 18-24 months. Treated patients frequently experience debilitating side effects, and many patients delay the start of antibiotic

diarrhea
rifampin
ethambutol
azithromycin
macrolides
  • 380 views
  • 04 Oct, 2022
  • 22 locations
Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact

has created the need for therapies aimed to modulate the overstated of host response. During the past 2 decades, macrolide molecules proved interest to be immunomodulatory agents; due beyond their

septic shock
procalcitonin
pneumonia
shock
cytokines
  • 0 views
  • 11 May, 2022
  • 1 location
CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

MAC lung infections are a growing public health problem. The ATS / IDSA 2007 guidelines for the treatment of these non-tuberculous mycobacterial infections recommend the use of a macrolide or

rifampin
rifabutin
azithromycin
ethambutol
tuberculosis
  • 252 views
  • 14 Feb, 2022
  • 1 location