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Found 686 clinical trials
Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003

A randomised trial for children with acute lymphoblastic leukemia, using the detection of minimal residual disease to define risk groups, aiming to answer the questions: 1. Can

residual tumor
remission
lymphoid leukemia
minimal residual disease
  • 9 views
  • 07 Nov, 2020
  • 1 location
COVID-19 Vaccination of Immunodeficient Persons (COVAXID)

The study is designed as an open, non-randomized, phase IV cohort study in which the mRNA vaccine Comirnaty will be given in two doses. Analyses will be performed on blood and saliva, investigating humoral and cellular vaccine responses. Occurence of local or systemic reactogenicity will be evaluated, as well as …

  • 0 views
  • 15 Mar, 2021
  • 1 location
High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)

The purpose of this study is to investigate the clinical efficacy of high-dose methotrexate consolidation therapy for adult patients with BCR-ABL-negative ALL.

etoposide
mercaptopurine
cyclophosphamide
doxorubicin
adult acute lymphocytic leukemia
  • 12 views
  • 07 Nov, 2020
  • 1 location
Multi-center Trial of Revlimid and Rituximab for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

The study is a two-arm, multi-center trial of Revlimid® and Rituximab, for the frontline treatment of patients with Chronic Lymphocytic Leukemia (CLL) designed and conducted by the CLL

neutrophil count
cancer
revlimid
platelet count
lymphoid leukemia
  • 42 views
  • 07 Nov, 2020
  • 3 locations
Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to determine whether Valproic acid, as a single agent is effective in the treatment of Chronic Lymphocytic Leukemia which has relapsed or is refractory to

neutrophil count
cancer
nucleoside analog
platelet count
lymphoid leukemia
  • 22 views
  • 07 Nov, 2020
  • 1 location
The Humanized Monoclonal Antibody Milatuzumab for Refractory Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to determine whether Milatuzumab is effective in patients with refractory chronic lymphocytic leukemia, and also to find out in which range of doses is a

cytopenia
monoclonal antibodies
lymphadenopathy
progressive disease
chronic lymphocytic leukemia refractory
  • 20 views
  • 07 Nov, 2020
  • 1 location
Efficacy and Safety of Nipent Cytoxan and Rituxan in the Treatment of Chronic Lymphocytic Leukemia.

This research study measures the safety and efficacy of the combination of three drugs that are approved, Nipent, Rituxan and Cytoxan in the treatment of Chronic Lymphocytic Leukemia (CLL

rituxan
lymphoid leukemia
  • 389 views
  • 07 Nov, 2020
  • 1 location
Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)

The purpose of this study is to investigate the efficacy and safety for treating adult ALL patients with the pediatric protocol.

mercaptopurine
cyclophosphamide
adult acute lymphocytic leukemia
lymphoid leukemia
cytarabine
  • 7 views
  • 07 Nov, 2020
  • 1 location
Study of Liposomal Annamycin in Patients With Refractory or Relapsed Acute Lymphocytic Leukemia

in patients with refractory or relapsed acute lymphocytic leukemia.

lymphoid leukemia
  • 26 views
  • 07 Nov, 2020
  • 1 location
Activity and Safety of Lenalidomide and Rituximab (LenRtx) as Non-chemotherapy Based Therapy for Patients With Chronic Lymphocytic Leukemia

The rationale for combining lenalidomide with rituximab derives from preclinical observations suggesting that lenalidomide may enhance the ADCC (antigen-dependent cellular cytotoxicity) triggered by monoclonal antibodies such as rituximab. Lenalidomide augments NK cytotoxicity by increasing CD56dimCD3 subset, in addition to inducing IL-2 in T cells. These results provide the cellular and …

chronic lymphocytic leukemia
monoclonal antibodies
lenalidomide
monoclonal protein
lymphoma
  • 18 views
  • 08 Nov, 2020
  • 1 location