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Found 52 clinical trials
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A Phase 2, Open-Label, Monotherapy, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement

This is an open-label, monotherapy study of INCB054828 in subjects with myeloid/lymphoid neoplasms with FGFR1 rearrangement.  Subjects will receive a once daily (QD) dose of INCB054828

myeloid neoplasm
FGFR1
lymphoid malignancy
  • 80 views
  • 14 Dec, 2020
  • 35 locations
A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib (INCB054828) in subjects with myeloid/lymphoid neoplasms with fibroblast growth factor receptor (FGFR) 1

  • 273 views
  • 07 Sep, 2021
  • 81 locations
Investigating Safety Tolerability Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours

  • 16 views
  • 03 Sep, 2021
  • 20 locations
  • 0 views
  • 04 Jun, 2021
  • 1 location
A Phase 1 Study of SHR2554 in Subjects With Relapsed or Refractory Mature Lymphoid Neoplasms

, safety, pharmacokinetics, and preliminary anti-tumor activity of SHR2554 in participants with relapsed or refractory mature lymphoid neoplasms.

  • 5 views
  • 14 Feb, 2021
  • 1 location
The WWRD Study: AVM0703 for Treatment of Leukemia or Lymphoma

(IV) infusion to patients with lymphoid malignancies.

  • 0 views
  • 23 Sep, 2021
  • 5 locations
Sintilimab in Combination With Chidamide in Refractory and Relapsed ENKTCL

Extranodal natural killer/T cell lymphoma(ENKTCL) is a distinct lymphoid neoplasm with aggressive course and poor outcomes. Optimal treatment strategies for advanced ENKTCL have not been fully

  • 3 views
  • 24 Mar, 2021
  • 4 locations
Safety and Efficacy Study of TNX-650 to Treat Refractory Hodgkin's Lymphoma

The purpose of this study is to determine the safety and effectiveness of TNX-650 for Injection when administered to patients with refractory Hodgkin's lymphoma.

refractory hodgkin lymphoma
stanford v regimen
lymphoma
platelet count
  • 19 views
  • 07 Nov, 2020
  • 2 locations
First-in-Human Study of ICT01 in Patients With Advanced Cancer

Part 1 will be a dose escalation study of IV ICT01 (a monoclonal antibody targeting BTN3A) as monotherapy in patients with advanced solid or hematologic tumors, followed by a cohort examining the combination of ICT01 plus pembrolizumab (Keytruda). Part 2 will be a cohort expansion into 2-3 solid tumor indications …

leukemia
measurable disease
lymphoma
monoclonal antibodies
antibody therapy
  • 1 views
  • 04 May, 2021
  • 6 locations
Futibatinib in Patients With Specific FGFR Aberrations

-esophageal junction (GEJ) cancer harboring FGFR2 amplification; and patients with myeloid or lymphoid neoplasms with FGFR1 rearrangements.

  • 0 views
  • 23 Jul, 2021
  • 63 locations