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Found 716 clinical trials
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Efficacy and Safety of Nipent Cytoxan and Rituxan in the Treatment of Chronic Lymphocytic Leukemia.

This research study measures the safety and efficacy of the combination of three drugs that are approved, Nipent, Rituxan and Cytoxan in the treatment of Chronic Lymphocytic Leukemia (CLL

lymphoid leukemia
rituxan
  • 389 views
  • 07 Nov, 2020
  • 1 location
None
Multi-center Trial of Revlimid and Rituximab for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

The study is a two-arm, multi-center trial of Revlimid® and Rituximab, for the frontline treatment of patients with Chronic Lymphocytic Leukemia (CLL) designed and conducted by the CLL

rituximab
platelet count
neutrophil count
cancer
lenalidomide
  • 42 views
  • 07 Nov, 2020
  • 3 locations
None
Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to determine whether Valproic acid, as a single agent is effective in the treatment of Chronic Lymphocytic Leukemia which has relapsed or is refractory to

platelet count
cancer
neutrophil count
lymphoid leukemia
nucleoside analog
  • 22 views
  • 07 Nov, 2020
  • 1 location
None
The Humanized Monoclonal Antibody Milatuzumab for Refractory Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to determine whether Milatuzumab is effective in patients with refractory chronic lymphocytic leukemia, and also to find out in which range of doses is a

cytopenia
monoclonal antibodies
chronic lymphocytic leukemia refractory
progressive disease
lymphoid leukemia
  • 20 views
  • 07 Nov, 2020
  • 1 location
None
Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)

The purpose of this study is to investigate the efficacy and safety for treating adult ALL patients with the pediatric protocol.

ejection fraction
asparaginase
dexamethasone
vincristine
cytarabine
  • 7 views
  • 07 Nov, 2020
  • 1 location
None
Study of Liposomal Annamycin in Patients With Refractory or Relapsed Acute Lymphocytic Leukemia

in patients with refractory or relapsed acute lymphocytic leukemia.

lymphoid leukemia
  • 26 views
  • 07 Nov, 2020
  • 1 location
None
Safety and Efficacy of Curcumin in Children With Acute Lymphoblastic Leukemia

Assessment of of the biological effects of curcumin on microbiota in children with acute lymphoblastic leukemia

  • 0 views
  • 24 Sep, 2021
None
Activity and Safety of Lenalidomide and Rituximab (LenRtx) as Non-chemotherapy Based Therapy for Patients With Chronic Lymphocytic Leukemia

The rationale for combining lenalidomide with rituximab derives from preclinical observations suggesting that lenalidomide may enhance the ADCC (antigen-dependent cellular cytotoxicity) triggered by monoclonal antibodies such as rituximab. Lenalidomide augments NK cytotoxicity by increasing CD56dimCD3 subset, in addition to inducing IL-2 in T cells. These results provide the cellular and …

chronic lymphocytic leukemia
rituximab
lymphoma
monoclonal antibodies
lenalidomide
  • 18 views
  • 08 Nov, 2020
  • 1 location
None
Ofatumumab as Part of Reduced Intensity Conditioning (RIC) Regimen for Patients With High Risk Chronic Lymphocytic Leukemia (CLL) Undergoing Allogeneic Hematopoietic Cell Transplantation

A good proportion of patients with chronic lymphocytic leukemia (CLL) can be managed effectively with palliative chemotherapy. However, there is a group of younger patients with poor risk

hematologic malignancy
chronic lymphocytic leukemia
rituximab
monoclonal antibodies
richter syndrome
  • 12 views
  • 08 Nov, 2020
  • 2 locations
None
Eradication of Residual Disease by Preemptive Immunointervention After Allogeneic Hematopoietic Stem Cells Transplantation in Chronic Lymphocytic Leukemia

Usually Chronic lymphocytic leukemia (CLL) is a disease of the elderly patients. However, the diagnosis in young patients become more frequently with poor prognosis. The identification of

graft versus host disease
lymphoma
residual tumor
remission
fludarabine
  • 11 views
  • 07 Nov, 2020
  • 1 location