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Found 14313 clinical trials
Featured trial
The Impact of Emotions on Social Distancing Adherence and Caregiver Self-efficacy among Caregivers for individuals with Alzheimer’s disease or related dementias during the COVID-19 Pandemic

The purpose of this research study is to understand the factors (e.g., feeling unhappy, lonely, frustrated) that influence compliance with social distancing recommendations during the COVID-19 pandemic. In addition, this study aims to understand how negative emotions (e.g., feeling unhappy, lonely, frustrated) along with social distancing requirements influence family caregivers’ …

Accepts healthy volunteers
cognitive assessment
Online studies
dementia
  • 1175 views
  • 04 Mar, 2022
  • 1 location
  • Online study
Featured trial
Live Discharge from Hospice Care

This is a research opportunity across the US for patients and caregivers who are being discharged from hospice care. The purpose is to understand what happens in the six months following a live discharge from hospice care through a series of interviews with patients and caregivers. Participation in the study …

alzheimer's disease
Online studies
Accepts healthy volunteers
  • 189 views
  • 03 Mar, 2022
  • 1 location
  • Online study
Featured trial
Study to evaluate HZN-825 in patients with Idiopathic Pulmonary Fibrosis (IPF)

daily (QD) or twice daily (BID)) or a placebo regimen for 52 weeks. Participants who complete the duration of this trial may be eligible to enter an open-label 52-week extension trial where all patients

pneumonia
diffusion capacity of the lung for carbon monoxide
emphysema
  • 8 views
  • 14 Jul, 2022
  • 20 locations
Featured trial
A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)

>All the people who decide to join the Together Study will at some point receive the investigational medication (called bepranemab).  

mild cognitive impairment
amyloid
dementia
cognitive assessment
mini-mental state examination
  • 65 views
  • 29 Jul, 2022
  • 86 locations
Featured trial
A Trial Evaluating Different Dosing Durations of TEPEZZA® Treatment in Patients with Thyroid Eye Disease (TED)

The overall objective is to investigate the safety, tolerability and need for re-treatment of 3 different TEPEZZA® treatment durations (4, 8, or 16 infusions) in patients with TED.

  • 8 views
  • 23 Jul, 2022
  • 13 locations
Featured trial
A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

This is a nonrandomized study of ruxolitinib in combination with a standard multi-agent chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will

mercaptopurine
dexamethasone
pegaspargase
cyclophosphamide
asparaginase
  • 0 views
  • 22 Jul, 2022
  • 98 locations
Featured trial
Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies

The study will determine Recommended Phase 2 Dose for all study drugs, based on the safety and tolerability of the following combinations: INCAGN02385 + INCAGN02390 and INCAGN02385 +

BRAF
immunologic adjuvant
pd-1 inhibitor
  • 0 views
  • 20 Jul, 2022
  • 5 locations
Featured trial
Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

acute coronary syndrome
revascularisation
coronary revascularization
  • 1647 views
  • 05 Feb, 2021
  • 1 location
Featured trial
A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL) (topMIND)

The purpose of this single-arm, open-label, Phase 1b/2a, multicenter basket study is to evaluate whether tafasitamab and parsaclisib can be safely combined at the recommended Phase 2 dose (RP2D) and dosing regimen that was established for each of the 2 compounds as a treatment option for adult participants with R/R …

btk inhibitor
anti-cd20 antibody
lymphoma
chronic lymphocytic leukemia
leukemia
  • 2 views
  • 09 Aug, 2022
  • 40 locations
Featured trial
Study to evaluate HZN-825 in patients with Diffuse Cutaneous Systemic Sclerosis (dcSSc)

(administered once daily (QD) or twice daily (BID)), or a placebo regimen for 52 weeks.Participants who complete all study visits may be eligible to enter a 52-week extension study where

MRSS
diffuse cutaneous systemic sclerosis
raynaud's phenomenon
raynaud's syndrome
rheumatism
  • 10 views
  • 09 Jul, 2022
  • 49 locations