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Found 38 clinical trials
Study Evaluating the Safety and Efficacy of C-CHOP in Untreated Subjects With Angioimmunoblastic T Cell Lymphoma

This is a single-arm, open-label phase 2study of Chidamide in combination with CHOP in the treatment of subjects with untreated angioimmunoblastic T cell lymphoma.

doxorubicin
vincristine
lymphoma
measurable disease
prednisone
  • 0 views
  • 23 Jan, 2021
Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

This partially randomized clinical trial studies cholecalciferol in improving survival in patients with newly diagnosed cancer with vitamin D insufficiency. Vitamin D replacement may improve tumor response and survival and delay time to treatment in patients with cancer who are vitamin D insufficient.

doxorubicin
treatment regimen
large cell lymphoma
cyclin d1
angioimmunoblastic t-cell lymphoma
  • 87 views
  • 13 Apr, 2021
  • 2 locations
Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to explore CDZ173, a selective PI3K inhibitor, in patients with genetically activated PI3K, i.e., patients with APDS/PASLI. The study consists of two parts. Part I is the open label part designed to establish the safety and pharmacokinetics of CDZ173 in the target population, as well as …

  • 0 views
  • 13 Jun, 2021
  • 12 locations
Application of 68Ga NEB PET Imaging in the Diagnosis and Evaluation of Lymphatic Disorders

, lymphangioleiomyomatosis, plastic bronchitis, lymphadenopathy caused by rheumatoid arthritis, etc.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Sildenafil for the Treatment of Lymphatic Malformations

A Phase 2 study to evaluate safety and efficacy of sildenafil taken orally to improve or resolve lymphatic malformations in children. Subjects may receive either placebo or treatment in an oral dosage with an open label extension for subjects who received placebo. The study treatment assignment will be randomized in …

  • 53 views
  • 24 Jan, 2021
  • 3 locations
Rituximab Combined With Chidamide and Lenalidomide for r/r AITL

This study is designed to explore the effeicency and toxicities of rituximab combined with chidamide and lenalidomide in patients with relapsed or refractory AITL.

lenalidomide
growth factor
lymphoma
renal function
measurable disease
  • 0 views
  • 02 Apr, 2021
  • 1 location
Immunotherapy in Peripheral T Cell Lymphoma - the Role of Alemtuzumab in Addition to Dose Dense CHOP

Peripheral T cell lymphomas comprise 10-15% of all malignant lymphomas. The prognosis is significantly worse than that of aggressive B cell lymphomas. The prospects of elderly patients are especially poor, with an estimated disease free survival of only 25% after three years. Previous phase II trials have demonstrated a significant …

peripheral t-cell lymphoma
lymphoma
measurable disease
b-cell lymphoma
t-cell lymphoma
  • 10 views
  • 07 Nov, 2020
  • 1 location
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units

For the next 5-10 years or possibly longer, a high proportion of the Cord Blood Banks (CBB) inventory worldwide will be composed of unlicensed umbilical cord blood (UCB) units. While Food and Drug Administration (FDA)-licensed units will be prioritized, it will always be possible that an unlicensed unit will have …

  • 24 views
  • 29 Jan, 2021
  • 1 location
BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Adult T-cell leukemia/lymphoma (ATLL) is a rare form of cancer found mostly among people from the Caribbean islands, Western Africa, Brazil, Iran, and Japan. Most cases of this disease in the United States occur along the East Coast due to emigration from the Caribbean islands. There is currently no standard …

doxorubicin
chemotherapy regimen
lymphoma
vincristine
leukemia
  • 113 views
  • 29 May, 2021
  • 3 locations
Phase I/II Study Evaluating AUTO4 in Patients With TRBC1 Positive T Cell Lymphoma

The purpose of this study is to test the safety and efficacy of AUTO4 a CAR T cell treatment targeting TRBC1 in patients with relapsed or refractory TRBC1 positive selected T-Non-Hodgkin Lymphoma.

large cell lymphoma
neutrophil count
lymphoma
measurable disease
fludarabine
  • 35 views
  • 26 Jan, 2021
  • 5 locations