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Found 136 clinical trials
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ABUS for Early-stage Breast Cancer

axillary US to predict axillary lymph node metastasis before surgery, in combination with preoperative breast US, in many institutions. However, recent studies have reported that sentinel lymph node biopsy

  • 0 views
  • 26 Jan, 2021
  • 3 locations
None
A Study on Tumor Budding Guiding Individualized Surgical Planning of Early-stage Oral Squamous Cell Carcinoma.

The purpose of this study is to determine whether cervical lymph node dissection is necessarily performed in the presence of early-stage oral squamous cell carcinoma.

metastasis
  • 8 views
  • 21 Jan, 2021
  • 1 location
None
Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer

This clinical trial is designed to be a multi-center prospective, parallel-controlled Phase III clinical study. In this study, the efficacy of tamoxifen versus toremifene shall be compared in CYP2D6 intermediate/poor metabolizers of premenopausal patients with estrogen receptor-positive early breast cancer.

toremifene
estrogen receptor
mastectomy
cancer
breast cancer
  • 28 views
  • 21 Jan, 2021
  • 18 locations
None
Clinical Significance of Supraclavicular Lymph Node Dissection for Breast Cancer Patients With Ipsilateral Supraclavicular Lymph Node Metastasis

Breast cancer patients with ipsilateral supraclavicular lymph node metastasis are defined as c stage (N3) according to the newly published 8th AJCC TNM staging system. No concret guide line was

  • 0 views
  • 27 Apr, 2021
  • 1 location
None
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy

Treatment for Low rectal cancer, especially in patients with regional lymph node metastasis are quite different between Japanese guideline (JSCCR) and western countries' guideline (NCCN, ESMO

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
[18F] Fluorocholine FCH Positron Emission Tomography (PET)/Computed Tomography (CT) for Detection of Prostate Cancer Lymph Nodes Metastases

The objective of this trial is to assess the value of 18F-choline PET/CT for the detection of regional lymph node metastases from prostate cancer. In addition, the investigators want to

pet/ct scan
prostate specific antigen
choline
metastasis
ct scan
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
Interest of PET Imagery With 18-FDG in the Extension Assessment of the Cervical Cancer

specificity for the detection of such lymph node metastasis with a sensitivity varying from 24 to 75 % and a specificity between 84 and 100 % according to the studies. As for the use of an 18-FDG

carcinoma
cancer
lymphadenectomy
cervical carcinoma
metastasis
  • 4 views
  • 07 Nov, 2020
  • 1 location
None
Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma

unknown primary melanoma patients with RECIST 1.1 measurable de-novo or recurrent disease (short axis lymph node metastasis 1.5cm). NanoString IFN-gamma signature high patients will be randomized

  • 1 views
  • 25 Jan, 2021
  • 1 location
None
TIP (Paclitaxel + Ifosfamide + Cisplatin) Combined With Nimotuzumab & Triprilimab as Neoadjuvant Treatment in Locally Advanced Penile Cancer

Primary Objective:To evaluate the efficacy and safety of TIP (paclitaxel + ifosfamide + cisplatin) combined with nimotuzumab & triprilimab as neoadjuvant treatment in locally advanced penile cancer.

  • 1 views
  • 24 Jan, 2021
  • 1 location
None
Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

To explore the feasibility of target biopsy of carbon nanoparticles labelled lymph node after neoadjuvant systemic therapy for cN+ breast cancer, and evaluate whether it can accurately predict axillary lymph node status after neoadjuvant systemic therapy.

  • 0 views
  • 30 Jan, 2021
  • 1 location