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Found 51 clinical trials
Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer (RIBOLARIS)

This is an open-label, multicenter international trial in men and women with primary operable HR+/HER2-, ki67≥20%, grade 2 or 3 and stage II breast cancer to evaluate safety and long-term efficacy of a non-chemo treatment in patients biologically responders to neoadjuvant ribociclib and letrozole. This study aims to evaluate whether …

  • 0 views
  • 26 Jul, 2022
  • 17 locations
Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH)

described and oocyte donation is often offered as their only option to achieve pregnancy. Recently, evidence has emerged that supplementation with a specific hormone, luteinizing hormone (LH

luteinizing hormone
body mass index
antral follicle count
antral
ovarian stimulation
  • 0 views
  • 01 Sep, 2021
  • 3 locations
Role of Triptorelin 0.1 mg as a Luteal Phase Support in Assisted Reproductive Technique After Embryo Transfer : a Randomized Controlled Trial

(P) and estradiol (E2). The LP defect was primarily caused by reduced early-mid-luteal luteinizing hormone (LH) activity, resulting in a significant reduction in progesterone output by the corpora

Accepts healthy volunteers
  • 0 views
  • 27 May, 2022
  • 1 location
Can Biotin Supplementation be Used to Mask hCG Abuse? (hCG)

This sponsor is an anti-doping laboratory tasked with testing athlete samples for prohibited substances by the World Anti-Doping Agency and other agencies. This study is intended to measure: Urinary/serum hCG (human chorionic gonadotropin) and urinary biotin concentrations in both treatment groups before, during, and after hCG intervention using standard immunoassay …

Accepts healthy volunteers
  • 0 views
  • 29 Jul, 2022
  • 1 location
  • 5 views
  • 23 Sep, 2022
  • 88 locations
Prolonged Protocol of Early Follicular or Mid Luteal Phase

advantages in achieving ideal egg number, increasing endometrial receptivity to embryo transfer, inhibiting endogenous luteinizing hormone (LH) peak and reducing cycle cancellation rate. The full dose of

polycystic ovary syndrome
ovarian hyperstimulation
controlled ovarian hyperstimulation
gonadotropin
antral follicle count
  • 41 views
  • 24 Jan, 2021
  • 1 location
Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer (POLAR)

modulator (such as tamoxifen) or an aromatase inhibitor (anastrozole, letrozole, exemestane) or fulvestrant (Faslodex). Premenopausal women and men may also receive a drug called an LHRH (luteinizing

estrogen
endocrine therapy
estrogen receptor
HER2
letrozole
  • 3 views
  • 19 Feb, 2022
  • 55 locations
PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA) (PALMIRA)

Hormone Receptor (HR)-positive/Human Epidermal Growth Factor Receptor 2 (HER2)-negative advanced breast cancer (ABC)

letrozole
tamoxifen
estradiol
fulvestrant
lhrh analogue
  • 90 views
  • 30 Apr, 2022
  • 51 locations
Pozzi Forceps in Intrauterine Insemination

Many infertility and subfertility issues are treated nowadays with intrauterine inseminations. This is a minimally invasive technique that consists in placing sperm into a woman's uterus. Inseminations have only a fair success rate despite advances in technology ( 7 % per cycle). The goal of this study is to find …

letrozole
unexplained infertility
endometriosis
intrauterine insemination
secondary infertility
  • 106 views
  • 25 Feb, 2022
  • 1 location
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET

The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the live birth rate in women undergoing …

gonadotrophin releasing hormone analogue
gonadorelin
  • 9 views
  • 27 May, 2022
  • 1 location