Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 38 clinical trials
featured
Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

  • 926 views
  • 25 Mar, 2021
  • 12 locations
Synergetic B-cell Immunomodulation in SLE - 2nd Study.

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

azathioprine
belimumab
nephritis
mycophenolate
rituximab
  • 10 views
  • 07 Mar, 2021
  • 4 locations
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 96 views
  • 25 Mar, 2021
  • 1 location
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

angiotensin
mycophenolic acid
mammogram
kidney biopsy
antinuclear antibody
  • 0 views
  • 28 Jul, 2021
  • 66 locations
Safety Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

with moderately active lupus nephritis.

hydroxychloroquine
body mass index
systemic lupus erythematosus
methotrexate
corticosteroids
  • 124 views
  • 25 Jul, 2021
  • 26 locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

angiotensin
proteinuria
lupus
immunosuppression
nephropathy
  • 0 views
  • 08 Jul, 2021
  • 30 locations
A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

This is a Phase 1b/2, multi-center study in which patients will receive KZR-616, administered as a subcutaneous (SC) injection weekly for 13 weeks (Phase 1b) or 24 weeks (Phase 2).

body mass index
mammogram
lupus
azathioprine
antinuclear antibody
  • 261 views
  • 10 May, 2021
  • 39 locations
Study of Safety Efficacy and Tolerability of Secukinumab Versus Placebo in Combination With SoC Therapy in Patients With Active Lupus Nephritis

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

urinary sediment
glomerular filtration rate
mammogram
nephritis
  • 37 views
  • 28 Jul, 2021
  • 123 locations
Daratumumab to Treat Active Lupus Nephritis

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupus nephritis.

remission
nephritis
proteinuria
mammogram
  • 0 views
  • 30 May, 2021
  • 1 location
The Iguratimod Effect on Lupus Nephritis (IGeLU)

This study is a 52-week, randomized, open, active-controlled trial of patients with active diffused lupus nephritis, to assess the efficacy and safety of a novel chemical synthetic agent

proteinuria
azathioprine
cyclophosphamide
prednisone
nephritis
  • 43 views
  • 22 Jan, 2021
  • 2 locations