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Found 119 clinical trials
A Clinical Study of Intravenous T3011 Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

This is a Phase 1/2a open label study to evaluate the safety and preliminary efficacy of intravenous T3011 given alone and in combination with intravenous pembrolizumab in participants with advanced or metastatic solid tumors.

measurable disease
pembrolizumab
metastasis
  • 0 views
  • 02 Sep, 2021
  • 4 locations
Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients …

stereotactic radiation
cancer
ct scan
lung cancer
metastasis
  • 5 views
  • 28 Feb, 2022
  • 1 location
Papaverine and Stereotactic Body Radiotherapy (SBRT) for Non Small Cell Lung Cancer (NSCLC) or Lung Metastases

This phase I trial studies the side effects and how well papaverine hydrochloride and stereotactic radiation therapy body (SBRT) work in treating patients with non-small cell lung cancer. Papaverine hydrochloride may help radiation therapy work better by making tumor cells more sensitive to the radiation therapy. Stereotactic body radiation therapy …

solid tumour
metastasis
stereotactic body radiation therapy
ct scan
  • 0 views
  • 01 Jul, 2022
  • 1 location
DCE-CT of Thoracic Tumors as an Early Biomarker for Treatment Monitoring in Comparison With Morphologic Criteria

DCE-CT of thoracic tumors as an early biomarker for treatment monitoring in comparison with morphologic criteria. Rationale of the clinical investigation For the evaluation of response to anti-tumoral therapy in thoracic tumors, merely morphologic information is often not sufficient for early response evaluation as dimensions of the oncologic lesions are …

  • 0 views
  • 14 Feb, 2021
  • 1 location
Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

This study investigates fluorine-18-AlphaVBeta6-BP ([18F]-αvβ6-BP) as a Positron Emission (PET) imaging agent in Non-Small Cell Lung Cancer (NSCLC) patients with brain metastases. Investigators hypothesize that [18F]-αvβ6-BP PET/Computed Tomography (CT) is a sensitive tool for disease assessment in patients with metastatic NSCLC, including those with brain metastases.

fdg pet
cancer
lung cancer
brain metastases
lung carcinoma
  • 0 views
  • 08 Aug, 2022
  • 1 location
Surveillance AFter Extremity Tumor surgerY (SAFETY)

Following treatment for a primary extremity sarcoma, patients remain at risk for the development of local and systemic disease recurrence. Metastasis (distant recurrence) to the lung is the most frequent single location of disease recurrence in sarcoma patients, occurring in almost half of all patients. Therefore, careful post-operative surveillance is …

cancer chemotherapy
ct scan
sarcoma
chest ct
metastasis
  • 0 views
  • 27 Feb, 2022
  • 10 locations
NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

The NutriCare study aims to develop, implement, and evaluate the efficacy of an innovative intervention strategy (medically tailored meals plus nutrition counseling) to integrate nutrition into the standard of care for oncology to improve outcomes of vulnerable patients with lung cancer. The NutriCare study evaluates the efficacy of the intervention …

cancer treatment
cancer chemotherapy
lung carcinoma
  • 0 views
  • 08 Aug, 2021
  • 4 locations
Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis

Radical treatment of primary rectal cancer with synchronous distant metastases includes surgical resection of primary and metastatic lesion. However, primary rectal cancer in case of metastasized disease are often locally advanced disease and need downsizing before surgery. It is reported that pelvic recurrence rates and distant metastasis rates outside liver …

neutrophil count
leucovorin
oxaliplatin
cetuximab
fluorouracil
  • 26 views
  • 23 Jan, 2021
  • 2 locations
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

The purpose of the study is to see if stereotactic radiosurgery/SRS is an effective treatment for people with a new diagnosis of brain metastases from small cell lung cancer/SCLC.

lung cancer
brain metastases
cancer
lung carcinoma
  • 0 views
  • 14 Jul, 2022
  • 7 locations
Pembro+Chemo in Brain Mets

The goal of this study is to evaluate whether providing Pembrolizumab prolongs survival and preserves quality of life while minimizing side effects for patients with NSCLC with untreated asymptomatic brain metastasis.

primary cancer
pemetrexed
brain metastases
taxane
cancer
  • 0 views
  • 21 Mar, 2022
  • 1 location