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Found 203 clinical trials
Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)

ameliorate autoantibody-mediated pulmonary injury. Anecdotal pilot studies indicate these treatments have significant benefit for a disease syndrome that has, until now, been almost invariably inexorable

  • 33 views
  • 25 Mar, 2022
  • 6 locations
Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD) (MOVE-COPD)

COPD is characterized by lung injury and inflammation caused by noxious particles and gases, including those emanating from cigarette smoke and air pollution. Despite the clear detrimental

carbon monoxide
cigarette smoke
  • 17 views
  • 10 Feb, 2022
  • 1 location
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Ulinastatin) II

association between decreased release of inflammatory response to urinary trypsin inhibitor treatment and decreased myocardial and lung injury after acute aortic syndrome surgery.

artery diseases
  • 0 views
  • 22 Aug, 2021
  • 2 locations
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis (GKT137831)

phosphate (NADPH) oxidase (NOX) isoforms. The investigators hypothesize the drug will decrease pulmonary injury due to reactive oxygen species (ROS) generated by NOX enzymes, which are believed to play an

idiopathic pulmonary fibrosis
forced vital capacity
pulmonary disease
  • 26 views
  • 02 May, 2022
  • 1 location
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

ventilator-induced lung injury, morbidity and mortality rates for babies with severe CDH remain high. The rationale for fetal therapy in severe CDH is to promote adequate lung growth for neonatal survival

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) (COVEN)

Electrical Impedance Tomography (EIT) in reducing daily lung injury score in patients with acute respiratory distress syndrome caused by COVID-19. The two strategies incorporate different prioritizations of

positive end-expiratory pressure
positive end expiratory pressure
SARS
mechanical ventilation
ventilator-induced lung injury
  • 0 views
  • 28 May, 2022
Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns (therapy)

failure. Various ventilation modes and strategies are used to optimize mechanical ventilation and prevent ventilator-induced lung injury. Among the important issues to be considered in newborns connected

  • 0 views
  • 27 Apr, 2022
  • 1 location
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques regarding: respiratory mechanics, gas exchange, changes in aeration, ventilation/perfusion matching its impact on cardiac function, especially the right heart (RH). The PEEP …

assisted breathing
pao2
positive end-expiratory pressure
positive end expiratory pressure
intubation
  • 31 views
  • 28 Feb, 2022
  • 1 location
Early Use of Prone Position in ECMO for Severe ARDS

Extracorporeal membrane oxygenation (ECMO) is widely used in the salvage treatment of critical acute respiratory distress syndrome (ARDS). However, reduce lung injury, accelerate lung recovery

assisted breathing
pao2
positive end expiratory pressure
mechanical ventilation
ventilator-induced lung injury
  • 2 views
  • 25 Feb, 2022
  • 1 location
Premedication for Less Invasive Surfactant Administration

delivery of surfactant to a spontaneously breathing infant through a thin catheter. This technique minimizes the risk for neonatal lung injury caused by positive pressure ventilation. LISA is nowadays

  • 0 views
  • 26 Jan, 2021
  • 1 location