Found 203 clinical trials
Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)
ameliorate autoantibody-mediated pulmonary injury. Anecdotal pilot studies indicate these treatments have significant benefit for a disease syndrome that has, until now, been almost invariably inexorable
- 33 views
- 25 Mar, 2022
- 6 locations
Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD) (MOVE-COPD)
COPD is characterized by lung injury and inflammation caused by noxious particles and gases, including those emanating from cigarette smoke and air pollution. Despite the clear detrimental
- 17 views
- 10 Feb, 2022
- 1 location
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Ulinastatin) II
association between decreased release of inflammatory response to urinary trypsin inhibitor treatment and decreased myocardial and lung injury after acute aortic syndrome surgery.
- 0 views
- 22 Aug, 2021
- 2 locations
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis (GKT137831)
phosphate (NADPH) oxidase (NOX) isoforms. The investigators hypothesize the drug will decrease pulmonary injury due to reactive oxygen species (ROS) generated by NOX enzymes, which are believed to play an
- 26 views
- 02 May, 2022
- 1 location
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)
ventilator-induced lung injury, morbidity and mortality rates for babies with severe CDH remain high. The rationale for fetal therapy in severe CDH is to promote adequate lung growth for neonatal survival
- 0 views
- 16 May, 2022
- 1 location
Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) (COVEN)
Electrical Impedance Tomography (EIT) in reducing daily lung injury score in patients with acute respiratory distress syndrome caused by COVID-19. The two strategies incorporate different prioritizations of
- 0 views
- 28 May, 2022
Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns (therapy)
failure. Various ventilation modes and strategies are used to optimize mechanical ventilation and prevent ventilator-induced lung injury. Among the important issues to be considered in newborns connected
- 0 views
- 27 Apr, 2022
- 1 location
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques regarding: respiratory mechanics, gas exchange, changes in aeration, ventilation/perfusion matching its impact on cardiac function, especially the right heart (RH). The PEEP …
- 31 views
- 28 Feb, 2022
- 1 location
Early Use of Prone Position in ECMO for Severe ARDS
Extracorporeal membrane oxygenation (ECMO) is widely used in the salvage treatment of critical acute respiratory distress syndrome (ARDS). However, reduce lung injury, accelerate lung recovery
- 2 views
- 25 Feb, 2022
- 1 location
Premedication for Less Invasive Surfactant Administration
delivery of surfactant to a spontaneously breathing infant through a thin catheter. This technique minimizes the risk for neonatal lung injury caused by positive pressure ventilation. LISA is nowadays
- 0 views
- 26 Jan, 2021
- 1 location