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Found 204 clinical trials
Treatment of ARDS With Sivelestat Sodium (TOAWSS)

process of ARDS and alleviate lung injury. Siverestat sodium is a specific inhibitor of NE, which has been proved by basic and observational clinical studies to be effective in alleviating lung injury of

  • 0 views
  • 29 Apr, 2022
  • 1 location
Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

The goal of this study is to investigate the efficacy of [68Ga]CBP8 to detect collagen deposition in radiation induced tissue injury.

pulmonary resection
lung resections
cancer chemotherapy
pdac
probe
  • 0 views
  • 26 Mar, 2022
  • 1 location
Smoking Cessation and Functional CT Assessment

The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.

cotinine
sildenafil 20 mg
forced expiratory volume
COPD
Accepts healthy volunteers
  • 157 views
  • 02 Mar, 2022
  • 1 location
Open Lung Strategy During Non-Invasive Respiratory Support of Very Preterm Infants in the Delivery Room

The opening and aeration of the lung is critical for a successful transition from fetal to neonatal life. Early nasal CPAP in the delivery room in spontaneously breathing premature babies with a gestational age of 30 weeks or less is a standard treatment approach since it reduces the need for …

assisted ventilation
mechanical ventilation
  • 0 views
  • 27 Sep, 2021
  • 2 locations
Nasal High-frequency Oscillatory Ventilation (NHFOV) for Ventilated Newborn Infants With BPD

). However, it is also related to increased risks of ventilator-associated lung injury and escalation of pulmonary inflammation, and which finally result in bronchopulmonary dysplasia (BPD). Early weaning

  • 0 views
  • 04 Jun, 2021
  • 1 location
Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant (HSCT)

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy, and lung injury affects as many as 25% of children receiving HSCT. Improved transplant techniques and major

  • 0 views
  • 26 Mar, 2022
  • 1 location
Phase 1/2 Study of SBRT With or Without GC4711 for NSCLC

GTI-4711-101 is a Phase 1-2 study of the safety of GC4711, and its potential to reduce radiation-related pulmonary injury due to SBRT for early stage large or central localized NSCLC. After an

measurable disease
  • 0 views
  • 22 Mar, 2022
  • 10 locations
Assessment of Continuous Positive Airway Pressure Therapy in IPF (ACT-IPF)

The purpose of this study is to evaluate whether biomarkers of lung injury and remodeling are responsive to effective continuous positive airway pressure (CPAP) treatment in adults with

fibrosis
pulmonary fibrosis
idiopathic pulmonary fibrosis
  • 0 views
  • 13 Apr, 2022
  • 1 location
The Role of Hyperoxia in Acute Ischemic Stroke

setting. The study will evaluate the effects of hyperoxia in stroke patients on the production of markers of free radical damage and inflammatory markers associated with hyperoxic lung injury.

ischemic stroke
  • 0 views
  • 28 Apr, 2022
  • 1 location
The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19 (ENDCOV-I)

Nintedanib on slowing the rate of lung disease in patients who have been diagnosed with COVID-19, and have ongoing lung injury more than 30 days out from their diagnosis.

assisted ventilation
fibrosis
nintedanib
bronchiectasis
interstitial lung disease
  • 0 views
  • 05 May, 2022
  • 8 locations