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Found 203 clinical trials
Hyperbaric Oxygen in the Prevention of Radiation Pneumonitis

Radiotherapy is one of the important treatments to improve the survival rate of breast cancer patients, but also has the risk of radiation lung injury, which can develop into pulmonary fibrosis

chest ct scan
  • 0 views
  • 07 Apr, 2022
  • 1 location
N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.

This study will evaluate the use of N-acetyl cysteine in post-reperfusion pulmonary injury in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary balloon angioplasty

endarterectomy
balloon angioplasty
  • 0 views
  • 26 Jan, 2021
  • 1 location
Intra-tracheal Instillation of Budesonide to Prevent Chronic Lung Disease (STOPCLD)

as vehicle would facilitate its delivery to the periphery of the lung and would inhibit lung inflammation and mitigate acute lung injury.

  • 0 views
  • 14 May, 2022
  • 1 location
Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery

This study is a randomized, double-blinded, controlled design. In this study, low doses of S-ketamine were selected for surgury treatment in septic patients under general anesthesia , Meanwhile, activity of HO-1 protein , oxidative stress and inflammatory markers in serum are measured to evaluating the effects of S-ketamine Anesthetic on …

inflammatory response
abdominal surgery
sepsis
anesthesia
  • 0 views
  • 06 Sep, 2021
  • 1 location
Clinical Decision Support Tool in PARDS Pilot Study

Previous clinical trials in adults with acute respiratory distress syndrome (ARDS) have demonstrated that ventilator management choices can improve Intensive Care Unit (ICU) mortality and shorten time on mechanical ventilation. This study seeks to scale an established Clinical Decision Support (CDS) tool to facilitate dissemination and implementation of evidence-based research …

mechanical ventilation
acute respiratory distress
assisted breathing
  • 0 views
  • 16 Aug, 2021
  • 8 locations
Safety and Efficacy Evaluation of CO2 Removal in Combination With Continuous Veno-Venous Hemodialysis/Hemodiafiltration Therapy (multiECCO2R)

Objective of the study is to assess the safety and efficacy of CO2 removal by the multiECCO2R (CO2 Removal System) on the multiFiltrate/multiFiltrate Pro in veno-venous extracorporeal circulation during continuous renal replacement therapy (CRRT) in patients presenting with hypercapnia due to acute lung failure and acute kidney injury.

renal replacement therapy
hemodiafiltration
positive end expiratory pressure
FIO2
  • 0 views
  • 07 Apr, 2022
A Study About Safety and Efficacy of Pirfenidone to Treat Grade 2 or Grade3 Radiation-induced Lung Injury.

Using Pirfenidone to treat Grade 2 or Grade3 radiation-induced lung injury, and observe the efficacy and safety of the drug.

  • 1 views
  • 10 Feb, 2022
  • 1 location
Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

This is a prospective, randomized, two-arm, controlled 30-day investigational pilot trial using the gammaCore Sapphire S non-invasive vagus nerve stimulation (nVNS) device + standard of care (SOC) in newly-hospitalized patients with mild-to-moderate traumatic brain injury (TBI) to prevent the progression towards immunokine storms, systemic inflammatory response syndrome (SIRS), severe respiratory …

mechanical ventilation
traumatic brain injury
inflammatory response
coma
assisted ventilation
  • 0 views
  • 09 Dec, 2021
  • 1 location
Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants (OPEN4HFOV)

To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure Fraction of inspired Oxygen 100 / peripheral Oxygen Saturation, OSI = MAPxFiO2x100/SpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.

FIO2
  • 0 views
  • 28 Feb, 2022
  • 1 location
Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema

vascular dilatation to characterize emphysema susceptibility in a normal smoking population. The investigators will correlate DECT measures of perfusion with lung injury measured by single photon emission

forced expiratory volume
x-rays
ct scan
dect
cotinine
  • 66 views
  • 13 Feb, 2021
  • 1 location