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Found 4552 clinical trials
Featured trial
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …

  • 596 views
  • 09 Aug, 2022
  • 56 locations
Featured trial
  • 0 views
  • 23 Jul, 2022
  • 120 locations
Featured trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors

  • 0 views
  • 19 Jun, 2022
  • 16 locations
Featured trial
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

This is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary clinical efficacy of INCB106385 when given as monotherapy or in combination with INCMGA00012 in participants with selected CD8 T-cell-positive advanced solid tumors including SCCHN, NSCLC, ovarian cancer, CRPC, TNBC, bladder …

cancer of the ovary
cancer
bladder tumor
measurable disease
  • 17 views
  • 11 Jul, 2022
  • 19 locations
Featured trial
Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration (FIGHT-210)

This is an open-label, single arm study to study the safety, efficacy and tolerability of Pemigatinib when used on participants with squamous or nonsquamous NSCLC with a documented FGFR1-3 mutations or fusions/rearrangement who have progressed on prior therapies and have no available standard treatment options

metastasis
lung carcinoma
FGFR1
measurable disease
  • 0 views
  • 14 Jul, 2022
  • 1 location
Featured trial
Lung Nodules – Scheduled or Planned Biopsy

It's estimated that 1.5 million new cases of lung nodules are found per year in the United States. The goal in managing this condition is to rapidly identify and resect malignant nodules and avoid

  • 14 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Small cell lung cancer (SCLC) Receiving Zepzelca

People with SMALL CELL LUNG CANCER are asked to participate in a research study being conducted by Montefiore Medical Center.

lung carcinoma
  • 0 views
  • 06 Aug, 2021
  • 1 location
Featured trial
COPD Research Study for those with currently using inhaled medications (triple therapy) and have required an oral steroid for a flare in breathing 1-2 times in the last 12 months.

This investigational study is enrolling moderate to severe COPD subjects.   To qualify you must be on inhaled maintenance medications and have required oral steroids 1-2 times or a hospitalization in the last year.    Pulmonary function test will be performed and compensation will be provided for those who qualify.  

  • 144 views
  • 23 Nov, 2020
  • 1 location
Featured trial
SEVERE COPD?

North Carolina Clinical Research is enrolling adults 40+ living with severe to very severe COPD fora clinical research study comparing two approved medications. 

  • 0 views
  • 10 Jan, 2022
  • 1 location
Featured trial
COPD Exacerbation Research Study

Looking for patients at least 40 years of age who have been diagnosed with COPD and recently had several events of worsening of symptoms.  

  • 125 views
  • 23 Nov, 2020
  • 1 location