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Found 1908 clinical trials
Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

Non Small Cell lung cancer (NSCLC) remains the first cause of death by cancer in the World. For the patients presenting a NSCLC stage IV, the median of survival is about 15 months today. The

liver metastasis
cancer
gilbert's syndrome
pd-l1
metastasis
  • 22 views
  • 25 Jan, 2021
  • 46 locations
KN046 in Subjects With Advanced Squamous Non-small Cell Lung Cancer

This study is a randomized, double-blind, multicenter, phase III clinical study to compare the clinical efficacy and safety of KN046 plus paclitaxel and carboplatin versus placebo plus paclitaxel and carboplatin in subjects with advanced squamous NSCLC who have not previously received systemic treatment.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Lung Cancer Screening by Low Dose CT Scan in a French Department (DEP KP80)

Lung cancer is the leading cause of cancer death worldwide. The aims of this study were to assess the feasibility and effectiveness of a lung cancer screening pilot program with LD CT scan in a

  • 0 views
  • 23 Jan, 2021
  • 1 location
A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

-small cell lung cancer (NSCLC) with documented advanced or metastatic epidermal growth factor receptor (EGFR) mutation (Phase 1b expansion cohorts A, B and C), to estimate the antitumor activity of

epidermal growth factor
pemetrexed
lung carcinoma
erlotinib
platinum-based chemotherapy
  • 5 views
  • 09 Apr, 2021
  • 84 locations
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC.

lung carcinoma
stereotactic body radiation therapy
durvalumab
  • 68 views
  • 29 Mar, 2021
  • 219 locations
Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy

The purpose of this study is to improve early detection of treatable relapse of lung cancer and thereby improve survival and quality of life for the patients. The investigators will perform a

lung carcinoma
adjuvant chemotherapy
ct scan
liquid biopsy
cancer chemotherapy
  • 0 views
  • 26 Jan, 2021
  • 3 locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

cancer treatment
growth factor
stage iv non-small cell lung cancer
epidermal growth factor receptor
epidermal growth factor
  • 27 views
  • 11 Apr, 2021
  • 298 locations
Safety and Efficacy of Talactoferrin in Addition to Standard Chemotherapy in Patients With Non-small Cell Lung Cancer

-small cell lung cancer compared to the combination of paclitaxel and carboplatin alone

stage iv non-small cell lung cancer
carboplatin
paclitaxel
  • 10 views
  • 07 Nov, 2020
  • 1 location
Clinical Study of Oral cMET Inhibitor INC280 in Adult Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (Geometry Mono-1)

A phase II study to evaluate antitumor activity of oral cMET inhibitor INC280 in adult patients with EGFR wild-type, advanced non-small cell lung cancer (NSCLC) as measured by overall response

lung carcinoma
systemic therapy
alopecia
measurable disease
metastasis
  • 186 views
  • 06 Mar, 2021
  • 163 locations
Adjuvant Vinorelbine Plus Cisplatin (NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer

completely resected IB-IIIA non-small-cell lung cancer. The patients with completely resected stage IB to stage IIIA non-small cell lung cancer were randomly assigned to the group of vinorelbine

kidney function test
adjuvant chemotherapy
vinorelbine
carcinoma
serum bilirubin level
  • 4 views
  • 07 Nov, 2020
  • 1 location