Found 442 clinical trials
A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for Delta-Like Ligand 3 (DLL3).
To determine the maximum tolerated dose(s) (MTD) or the Recommended Dose for Expansion (RDE) and dosing regimen for further development of BI 764532. The MTDs will be defined based on the frequency of patients experiencing dose limiting toxicities (DLTs) during the MTD evaluation period in studied regimens. The RDE will …
- 10 views
- 15 May, 2022
- 9 locations
Phase 2 Study of TVB-2640 in KRAS Non-Small Cell Lung Carcinomas
This is a prospective one-arm, two-stage phase 2 trial of TVB-2640 in KRAS mutant NSCLC patients. 13 patients will be treated with a minimum of 1 cycle of TVB-2640 therapy over 8 weeks.
- 1 views
- 06 Mar, 2022
- 1 location
Fraction Dose Escalation of Split-course Adaptive Hypo-fractionated Concurrent Chemoradiotherapy in Locally Advanced Non-small Cell Lung Cancer
This prospective phase I study intends to explore the maximum tolerable single radiation dose for locally advanced non-small cell lung cancer patients undergoing radical concurrent radiochemotherapy at the same bioequivalent radiation dose
- 0 views
- 25 Jul, 2021
- 1 location
A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer
This is an open, multi-cohort, exploratory phase II study on the safety and efficacy of TQB3616 combined with Anlotinib hydrochloride capsules or standard chemotherapy in the treatment of advanced lung cancer.
- 0 views
- 29 Sep, 2021
- 7 locations
ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma (ABC-lung)
ETOP 15-19 ABC-lung is an international, multi-centre open-label, randomized phase II trial with two non-comparative parallel arms of atezolizumab plus bevacizumab with carboplatin-paclitaxel (Arm A) or atezolizumab, bevacizumab and pemetrexed (Arm B) in patients with stage IIIB-IV non-squamous non-small cell lung cancer (NSCLC) harbouring EGFR mutations after failure of standard …
- 42 views
- 24 Mar, 2022
- 17 locations
Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines
This implementation study will examine the best ways to refer heavy smokers to information about lung cancer screening.
- 0 views
- 26 Mar, 2022
Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung Cancer (REACH PC)
This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer and their families.
- 219 views
- 07 Apr, 2022
- 19 locations
PAlliative RAdioTherapy to Lung Cancer A Randomized Multicentre Phase III Study (PARAT)
The aim of this study is to examine if a shorter palliative radiotherapy fractionation scheme of 20 Gy / 4 F can reduce the early oesophageal toxicity compared to 30 Gy / 10 F in patients with lung cancer in performance status (PS) 0-2. Secondary aims are to examine the …
- 2 views
- 01 Feb, 2022
- 1 location
Breath Analysis to Diagnose Lung Cancer (CATOCOV)
Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.
- 1 views
- 09 Feb, 2022
- 5 locations
Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer (STEP PC)
This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer
- 8 views
- 03 Mar, 2022
- 3 locations