Found 67 clinical trials
NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before
- 114 views
- 08 Nov, 2020
- 1 location
Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy
In the setting of radiotherapy as part of breast-conservation therapy for patients with early stage breast cancer, the novel planning and delivery method of intensity modulated radiotherapy is an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may …
- 1 views
- 08 Nov, 2020
- 1 location
Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery (CAPTRANE)
treatment is often the first treatment of breast cancer. It can be conservative by performing a partial mastectomy (lumpectomy or quadrantectomy) or non-preservative by total mastectomy.
- 159 views
- 07 Feb, 2022
- 6 locations
Radiofrequency Ablation After Breast Lumpectomy (ABLATE)
The main purpose of the study is to study the effectiveness of using a technique called RadioFrequency Ablation (RFA) after the breast tumor has been surgically removed. Ablation means cells are destroyed. The RFA device creates heat that destroys any cells in the area around where the tumor is removed, …
- 4 views
- 08 Nov, 2020
- 1 location
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer
(mastectomy vs lumpectomy) as per standard of care guidelines.
- 12 views
- 22 Apr, 2022
- 1 location
An Investigator Initiated Study of Intra-Operative Radiation Therapy (IORT) Using the Xoft Axxent eBx System
Single arm, prospective, multi-center, non-randomized study of subjects treated with single fraction, intra-operative radiation therapy at the time of lumpectomy for early stage breast cancer.To
- 0 views
- 12 Sep, 2021
- 1 location
Prophylactic Irradiation to the Contralateral Breast for BRCA Mutation Carriers Undergoing Treatment for Breast Cancer
Women with BRCA germline mutations face a very high risk of developing breast cancer during their lives. It was shown that for carrier patients, breast conservation, comprising of lumpectomy
- 6 views
- 23 Jan, 2022
- 1 location
Single Step Lesion Annotation and Localization of Suspicious Breast Lesions
the implanted reflector. After excision of the breast lesion, the handheld reader can be used to immediately confirm removal of the reflector, present in the lumpectomy specimen, and subsequent
- 0 views
- 28 Apr, 2022
- 1 location
Selective Omission of Axillary Surgery in Triple-negative and HER2-positive Breast Cancer After NACT
patients who achieve pCR in breast after NACT determined by lumpectomy. The trial is designed as a prospective, single-center, single-arm study with a limited number of patients (N=136). Patients
- 0 views
- 05 May, 2022
- 1 location
Randomized Study of Elective Regional Lymph Node Irradiation in N1 Breast Cancer
This study evaluates the impact of elective regional lymph node irradiation on N1 breast cancer patients receiving post-lumpectomy radiotherapy and anthracycline plus taxane (AT)-based
- 0 views
- 24 Feb, 2022
- 1 location