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Found 79 clinical trials
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NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before

  • 100 views
  • 08 Nov, 2020
  • 1 location
Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy

In the setting of radiotherapy as part of breast-conservation therapy for patients with early stage breast cancer, the novel planning and delivery method of intensity modulated radiotherapy is an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may …

breast cancer staging
magnetic resonance imaging of breast
lumpectomy
partial breast irradiation
mammogram
  • 1 views
  • 08 Nov, 2020
  • 1 location
The PRECISION Trial (Profiling Early Breast Cancer for Radiotherapy Omission): A Phase II Study of Breast-Conserving Surgery Without Adjuvant Radiotherapy for Favorable-Risk Breast Cancer

This research study is a way of gaining new knowledge about whether patients can omit radiation treatment after undergoing a lumpectomy, also known as "breast conserving surgery". In this trial

  • 0 views
  • 26 Nov, 2020
  • 6 locations
Randomized Study of Elective Regional Lymph Node Irradiation in N1 Breast Cancer

This study evaluates the impact of elective regional lymph node irradiation on N1 breast cancer patients receiving post-lumpectomy radiotherapy and anthracycline plus taxane (AT)-based

cancer
taxane
breast-conserving surgery
immunostimulant
anthracyclines
  • 0 views
  • 01 Dec, 2019
  • 1 location
Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery

treatment is often the first treatment of breast cancer. It can be conservative by performing a partial mastectomy (lumpectomy or quadrantectomy) or non-preservative by total mastectomy.

  • 12 views
  • 19 May, 2019
  • 10 locations
Boost Use in Breast Conservation Radiotherapy

This is a two arm randomized study for patients who are undergoing radiotherapy following breast conservation surgery for breast cancer. Local recurrence of breast cancer will be compared for patients receiving boost or no boost radiotherapy.

ductal carcinoma
carcinoma in situ
cancer
breast cancer
carcinoma
  • 18 views
  • 07 Nov, 2020
  • 1 location
Radiofrequency Ablation After Breast Lumpectomy (ABLATE)

The main purpose of the study is to study the effectiveness of using a technique called RadioFrequency Ablation (RFA) after the breast tumor has been surgically removed. Ablation means cells are destroyed. The RFA device creates heat that destroys any cells in the area around where the tumor is removed, …

lumpectomy
  • 4 views
  • 08 Nov, 2020
  • 1 location
Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy

Breast cancer patients often receive systemic drugs as the initial curative treatment of their disease. The initial systemic therapy leads to a variable degree of tumor shrinkage. At present, there is no evidence-based consensus among breast surgeons on the optimal extent of resection after considerable tumor shrinkage and whether resection …

adjuvant therapy
hormone therapy
lumpectomy
erbb2
breast adenocarcinoma
  • 21 views
  • 08 Nov, 2020
  • 1 location
Stereotactic Image-Guided Neoadjuvant Ablative Radiation Then Lumpectomy

entire breast. This clinical trial will evaluate the effectiveness of conformal radiation therapy delivered only to the area in the breast where the lumpectomy will be performed. This

  • 3 views
  • 08 Nov, 2020
  • 1 location
Real-Time Assessment Of Breast Cancer Lumpectomy Specimen Margins With Nonlinear Microscopy

, but without first processing tissue to make slides. This study will determine if a NLM can be used to evaluate tissue during lumpectomy surgery for breast cancer in order to reduce the probability

breast surgery
progesterone receptor
breast-conserving surgery
ductal carcinoma in situ
estrogen receptor
  • 0 views
  • 05 Aug, 2020