Found 70 clinical trials
NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before
- 100 views
- 08 Nov, 2020
- 1 location
Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy
In the setting of radiotherapy as part of breast-conservation therapy for patients with early stage breast cancer, the novel planning and delivery method of intensity modulated radiotherapy is an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may …
- 1 views
- 08 Nov, 2020
- 1 location
Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
treatment is often the first treatment of breast cancer. It can be conservative by performing a partial mastectomy (lumpectomy or quadrantectomy) or non-preservative by total mastectomy.
- 12 views
- 22 Jan, 2021
- 10 locations
Boost Use in Breast Conservation Radiotherapy
This is a two arm randomized study for patients who are undergoing radiotherapy following breast conservation surgery for breast cancer. Local recurrence of breast cancer will be compared for patients receiving boost or no boost radiotherapy.
- 18 views
- 07 Nov, 2020
- 1 location
Radiofrequency Ablation After Breast Lumpectomy (ABLATE)
The main purpose of the study is to study the effectiveness of using a technique called RadioFrequency Ablation (RFA) after the breast tumor has been surgically removed. Ablation means cells are destroyed. The RFA device creates heat that destroys any cells in the area around where the tumor is removed, …
- 4 views
- 08 Nov, 2020
- 1 location
Stereotactic Image-Guided Neoadjuvant Ablative Radiation Then Lumpectomy
breast. This clinical trial will evaluate the effectiveness of conformal radiation therapy delivered only to the area in the breast where the lumpectomy will be performed. This study will
- 3 views
- 21 Jan, 2021
- 1 location
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer
(mastectomy vs lumpectomy) as per standard of care guidelines.
- 6 views
- 13 May, 2021
- 1 location
Prophylactic Irradiation to the Contralateral Breast for BRCA Mutation Carriers Undergoing Treatment for Breast Cancer
Women with BRCA germline mutations face a very high risk of developing breast cancer during their lives. It was shown that for carrier patients, breast conservation, comprising of lumpectomy
- 6 views
- 07 Nov, 2020
- 1 location
Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer
The purpose of the study is to evaluate the efficacy of a dedicated Magnetic Resonance guided High Intensity Focused Ultrasound (MR-HIFU) unit in ablating breast cancer by comparing MR imaging and pathologic specimen after resection. Single-center, single-arm, non-randomized trial
- 0 views
- 29 Mar, 2021
- 1 location
Partial Breast Irradiation With Interstitial High Dose Rate Brachytherapy
Partial breast irradiation (PBI) is becoming more widespread in the treatment of early breast cancer in patients at low risk of relapse as pathological and clinical findings have demonstrated that most breast cancer recurrences after BCS occur close to the tumour bed. In our phase II prospective study PBI is …
- 0 views
- 07 Nov, 2020
- 1 location