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Found 82 clinical trials
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts A and B). 56 subjects have been planned for Part A and 76 subjects for Part B

Accepts healthy volunteers
cholesterol level
  • 0 views
  • 13 Jul, 2022
  • 1 location
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients (ACAV)

-density lipoprotein cholesterol (LDL-C) is very common after transplantation with nadir of LDL levels occurring at 6 months. Because of drug-drug interactions, heart transplant recipients cannot be

  • 1 views
  • 10 May, 2022
  • 1 location
Changes in Liver Fibrosis, Lipid Profile and Insulin Resistance in HCV Patients Who Received Antiviral Therapy

Hepatitis C virus (HCV) is one of the major globally cause of death and morbidity.Chronic hepatitis C is the leading cause of end-stage liver disease, hepatocellular carcinoma and liver-related death in Egypt.It could be considered a special type of metabolic diseases involving insulin resistance (IR) which accelerates fibrosis and modulation …

sofosbuvir
antiviral therapy
hepatic fibrosis
antiviral drugs
diabetes
  • 47 views
  • 17 Mar, 2022
  • 1 location
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism (HYPOCHOL)

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 24 Feb, 2022
  • 1 location
Effect of Diet Induced Ketosis on LDL Turnover Rates

There have been concerning case reports of marked elevations of LDL-c in some individuals consuming a KD and Dr. Lewis has been referred a number of these cases to his lipid clinic, some of whom have had extreme elevations of LDL that mimic familial hypercholesterolemia. These marked elevations of LDLc …

Accepts healthy volunteers
  • 22 views
  • 17 Nov, 2021
  • 1 location
ZOE METHOD Study: Comparing Personalized vs. Generalized Nutrition Guidelines

The ZOE Method Study will test the efficacy of personalized nutritional advice, delivered on an individual level through a digital device app; integrating dietary, lifestyle, physiological and metagenomic data, in improving certain cardiometabolic disease risk factors, compared to generalized nutrition advice (control).

Accepts healthy volunteers
  • 0 views
  • 14 Jun, 2022
  • 1 location
Topical Vancomycin Over Sternal Edge in Cardiac Surgery

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery. Vancomycin paste will be prepared using 2.5 g of vancomycin mixed with 2 ml normal saline. Vancomycin …

  • 0 views
  • 12 Sep, 2021
  • 1 location
Adjuvant Treatment in Elderly Patients With Periodontitis Through the Administration of a Supplement Rich in Oleuropein From the Olive Leaf (OLIVAGING)

Life expectancy has dramatically increased in the last century, although this process has not been always accompanied by an equivalent increase in healthy life expectancy. However, extending longevity without decreasing the risk of age-associated pathologies would not be desirable since non-communicable diseases can diminish seniors' quality of life, raise health-care …

chronic periodontitis
periodontal treatment
  • 0 views
  • 09 Aug, 2022
  • 1 location
  • 0 views
  • 09 Aug, 2022
  • 15 locations
  • 6 views
  • 11 Aug, 2022
  • 71 locations