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Found 10 clinical trials
Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity (LIFUS-Pharma)

blocker), lorazepam (GABAA positive allosteric modulator), nimodipine (calcium channel blocker), and dextromethorphan (glutamate N-Methyl-D-aspartate receptor antagonist). Single- and paired-pulse

Accepts healthy volunteers
  • 0 views
  • 08 Jun, 2022
  • 1 location
Enhanced Spatial Targeting in ECT Utilizing FEAST

The purpose of this research study is to find an alternative version of ECT that reduces the negative side effects (mainly memory loss) while still providing patients with relief from depressive symptoms. Previous forms of ECT may use Bilateral (electrodes on both sides of the head) or Right Unilateral (electrodes …

  • 0 views
  • 06 Jun, 2022
  • 1 location
De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients (DROP-Benzo)

, lorazepam) during anesthesia care. This occurs despite recommendations to avoid these medications in older patients due to associated medical risks and lack of demonstrated benefit. In other words, routine

  • 0 views
  • 07 Oct, 2022
  • 1 location
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

This phase II/IIII trial studies how well haloperidol and lorazepam work in controlling symptoms of persistent agitated delirium in patients with cancer that has spread to other places in the

advanced cancer
lorazepam
agitation
palliative care
haloperidol
  • 3 views
  • 09 Feb, 2022
  • 2 locations
Multi-modal Assessment of GABA Function in Psychosis (GABAmech)

dependent (BOLD) signal by fMRI after lorazepam. This study will enroll participants between the ages of 16 and 60, who have a psychotic illness (such as psychosis which includes conditions like

gamma-aminobutyric acid (gaba)
substance use disorder
remission
psychotic symptoms
suicide
  • 165 views
  • 12 Oct, 2022
  • 1 location
Ketamine for Pain Control After Severe Traumatic Injury

This study evaluates if the early utilization of ketamine infusion therapy among acutely injured adult trauma hospital inpatients with an ISS >15 will decrease the amount of opioid pain medication used as compared with placebo group. Ketamine infusion therapy initiated within 12 hours of hospital arrival will lead to decreased …

morphine
pain relieving
opioid
oral morphine
ketamine
  • 28 views
  • 22 Dec, 2021
  • 1 location
Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients (CARPZ-01)

Some patients with bipolar disorder show broad cognitive impairments (e.g. difficulty with concentration, problem solving, memory etc.) that persist during euthymia (no symptoms of depression or mania) despite remission of mood symptoms. Cognitive deficits (significant cognitive impairments) in bipolar disorder are associated with impairments in everyday functioning and quality of …

  • 0 views
  • 10 May, 2022
  • 2 locations
Blood Concentration in Lorazepam and Treatment in Adult Catatonia

infections (including HIV), typhoid fever, heat stroke, and autoimmune disease]. Benzodiazepines, especially LORAZEPAM, are the most common initial treatment, with a remission rate of approximately

  • 0 views
  • 26 Jan, 2021
  • 1 location
Pilot Study to Assess Heterogeneity of the Blood Brain Barrier in Patients With CNS Malignancy

This pilot research trial studies blood brain barrier differences in patients with brain tumors undergoing surgery. Studying samples of tissue and blood from patients with brain tumors in the laboratory may help doctors to understand how well drugs get into different parts of a brain tumor. This may help them …

nervous
MRI
primary brain tumors
brain metastases
metastasis
  • 0 views
  • 22 Oct, 2022
  • 1 location
Study of Postoperative Respiratory Complications in Children With Obstructive Sleep Apnea (PORC) (PORC)

Adenotonsillectomy is the first line surgical treatment for children with Obstructive Sleep apnea Syndrome (OSAS). Postoperative respiratory complications (PORC) may occur and are often related to co-morbidities. Despite guidelines from different scientific groups, there is no consensus on the monitoring requirements and management of PORC in these children.

  • 0 views
  • 04 Oct, 2022
  • 1 location