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Found 48 clinical trials
A Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

The main purpose of this study is to measure the amount of lopinavir/ritonavir (two anti-HIV medications) in the blood. Results from this study will be compared to the levels of the drugs

HIV Vaccine
lopinavir
lopinavir/ritonavir
kaletra
ritonavir
  • 340 views
  • 08 Nov, 2020
  • 56 locations
Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

The purpose of this study is to see if emtricitabine is safe in children infected with HIV and to determine the best dose.

lamivudine
emtricitabine
lopinavir/ritonavir
lopinavir
anti-hiv drugs
  • 151 views
  • 07 Nov, 2020
  • 2 locations
Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

The study will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.

hiv dna
hiv antibodies
antiretroviral therapy
lopinavir
antiretroviral agents
  • 94 views
  • 10 Nov, 2019
  • 49 locations
Efficacy of Favipiravir in Treatment of Mild & Moderate COVID-19 Infection in Nepal

COVID-19 has affected almost all countries in the world. Every other country is constantly working towards its treatment and development of vaccines, with little to no success so far. Recently, several regimens have been tried as antiviral medicine. Among these medicines, Favipiravir is considered a broad-spectrum antiviral with the spectrum …

  • 0 views
  • 10 Jan, 2021
  • 2 locations
Study of the 48-Week Virologic and Immunologic Response to Lopinavir/Ritonavir (Kaletra) in HIV Positive Adult Patients

Expected Enrollment: 40 patients Study Start Date: June 2005 Study Objectives: - To conduct a pilot study to assess the safety, tolerability, and antiviral activity of Kaletra 400/100 mg taken twice a day (bid) in antiretroviral (ARV)-naïve HIV-infected patients at Week 48 Primary Objectives: - To determine the proportion of …

kaletra
lopinavir
antiviral drugs
antiretroviral agents
hormonal contraception
  • 30 views
  • 07 Nov, 2020
  • 1 location
HIV Antiretroviral Drugs and Metabolism

will be studied before and at the end of four weeks of taking ritonavir, lopinavir/ritonavir or atazanavir/ritonavir. Hypothesis 2: NNRTI drugs do not increase HDL by increasing apo AI

efavirenz
lopinavir/ritonavir
lopinavir
ritonavir
atazanavir
  • 6 views
  • 07 Nov, 2020
  • 1 location
IFN Beta-1b and Ribavirin for Covid-19

As of 1 July 2020, more than 10 million people been confirmed to have infected by SARS-CoV-2, resulting in more than 500,000 deaths. No specific antiviral treatment for the SARS-CoV-2 is currently available, but existing medication could be repurposed. The investigators therefore propose to conduct an open-label randomized controlled trial …

critical illness
interferon
antiviral drugs
SARS
  • 0 views
  • 06 Aug, 2020
  • 1 location
IFN-beta 1b and Remdesivir for COVID19

A 5-day combination of interferon -1b and remdesivir will expedite the recovery, suppress the viral load and shorten hospitalisation in patients with SARS-CoV-2 infection compare to the control arm

  • 0 views
  • 17 Dec, 2020
  • 1 location
PI Vs. NNRTI Based Therapy for HIV Advanced Disease

Ritonavir boosted protease inhibitor based therapy will have equivalent antiviral efficacy over 48 weeks compared to NNRTI based therapy in patients who are antiretroviral therapy naïve and initiate therapy with CD4 counts ≤ 200/mm3.

antiviral
antiretroviral therapy
lopinavir
antiretroviral agents
protease
  • 32 views
  • 07 Nov, 2020
  • 5 locations
COVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavir

COVID-19 has rapidly evolved into a generalized global pandemic. Post-exposure prophylaxis (PEP) against on COVID-19 was identified as an urgent research priority by the WHO, and lopinavir

lopinavir
ritonavir
lopinavir/ritonavir
covid-19
  • 57 views
  • 07 May, 2020
  • 3 locations