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Found 14 clinical trials
A Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

The main purpose of this study is to measure the amount of lopinavir/ritonavir (two anti-HIV medications) in the blood. Results from this study will be compared to the levels of the drugs

lopinavir/ritonavir
lopinavir
ritonavir
kaletra
HIV Vaccine
  • 450 views
  • 08 Nov, 2020
  • 58 locations
Randomised Evaluation of COVID-19 Therapy (RECOVERY)

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only

lopinavir
covid-19
fever
influenza
pneumonia
  • 0 views
  • 19 Apr, 2022
  • 6 locations
Finding Treatments for COVID-19: A Phase 2 Multi-centre Adaptive Platform Trial to Assess Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

The trial will develop and validate a platform for quantitative assessment of antiviral effects in low-risk patients with high viral burdens and uncomplicated COVID-19 to determine in-vivo antiviral activity. In this randomized open label, controlled, group sequential adaptive platform trial, we will assess the performance of three distinct types of …

  • 0 views
  • 14 Sep, 2022
  • 2 locations
Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

The study will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.

hiv antibody
raltegravir
lopinavir
lopinavir/ritonavir
antiretroviral agents
  • 210 views
  • 10 Nov, 2021
  • 51 locations
Masitinib in Patients With Symptomatic Mild to Moderate COVID-19

The objective of the study is to evaluate the anti-viral efficacy of 3 different dosages of masitinib in patients with symptomatic mild to moderate COVID-19.

  • 0 views
  • 10 Jul, 2022
  • 5 locations
Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition

This study to investigate whether empiric use of an antibiotic with greater antimicrobial sensitivity (ceftriaxone) than standard-of-care (ampicillin plus gentamicin) will reduce mortality among HIV-infected/HEU children admitted to Mwanamugimu Nutrition Unit, Mulago Hospital, Kampala, Uganda.

  • 0 views
  • 08 Oct, 2021
  • 1 location
HIV-1 Infected Patients Phase II Trial Dual Combination Doravirine/Raltegravir Open Label

The objective of antiretroviral therapy (ART) is the maintenance of HIV viral suppression, the optimal condition to prevent disease progression, to optimize immune restoration, to prevent the development of viral resistance and to reduce viral transmission. Antiretroviral therapy has to be maintained long life over decades in the absence of …

  • 1 views
  • 12 Feb, 2021
  • 1 location
Registry of Management Strategies for Patients With COVID-19 in Healthcare Establishments

The purpose of the study is to describe medical care strategies implemented by healthcare establishments for patients affected by COVID-19

  • 0 views
  • 03 Nov, 2021
  • 1 location
Tolerability of Lopinavir Versus Dolutegravir for Children and Adolescents Living With HIV (LoDoCA)

Dolutegravir-based antiretroviral therapy is set to be increasingly replace ritonavir-boosted lopinavir-based regimens for the treatment of paediatric HIV. This prospective cohort study aims to

  • 0 views
  • 10 Aug, 2022
  • 1 location
Adverse Events Related to Treatments Used Against Coronavirus Disease 2019 (CovidTox)

used molecules, including but not limited to protease inhibitors (lopinavir/ritonavir), chloroquine, azithromycin, remdesivir and interferon beta-1a. Analyses of reports also include the International

azithromycin
lopinavir/ritonavir
lopinavir
covid-19
chloroquine
  • 10 views
  • 02 Mar, 2022
  • 1 location