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Found 8 clinical trials
Anal Manometry Examination in Patients With Ulcerative Colitis

function via manometry may help to give the appropriate treatment, such as biofeedback or pharmacological treatment such as loperamide or tricyclic anti-depressants. This may avoid escalation or replacing

remission
crohn's disease
loperamide
  • 0 views
  • 04 Oct, 2022
  • 1 location
Effect of Psyllium (Plantago Ovata) on Digestive Disorders in Familial Amyloidosis (Psyllium)

of loperamide. If this fails, treatment with a somatostatin analogue may be offered. However, all these treatments can present significant side effects, therefore natural alternatives are

  • 0 views
  • 25 Oct, 2022
  • 1 location
Role of Antisecretory Factor in Dihydropyrimidine Treatment of Colorectal Cancer (SALFLADMET)

in-hospital care including periods of support with iv fluids. The efficacy of current treatment for this adverse effect include iv fluids, loperamide and opioids po and octreotide sc is moderate and

  • 0 views
  • 04 Jun, 2022
  • 1 location
Prevention and Treatment of Pyrrolitinib-associated Diarrhea

prevention: Explore the recovery time of oral loperamide 4mg T.I.D. for pyrrolitinib induced diarrhea of 1-2 degrees. Secondary prevention: To explore the incidence of grade 3 and above diarrhea

  • 0 views
  • 10 Feb, 2021
  • 1 location
Targeting EGFR/ERBB2 With Neratinib in Hormone Receptor (HR)-Positive/HER2-negative HER2-enriched Advanced/Metastatic Breast Cancer

will take prophylactic loperamide with a stablished doses scheme during the firs cycle and on demand in subsequent cycles

estrogen receptor
endocrine therapy
erbb2
aromatase inhibitor
core needle biopsy
  • 0 views
  • 02 Aug, 2021
  • 15 locations
Fecal Microbiota Transplantation (FMT) for Immune-Checkpoint Inhibitor Induced-Diarrhea/Colitis in Genitourinary Cancer Patients

This trial studies how well fecal microbiota transplantation works in treating diarrhea or colitis (inflammation of the intestines) that is caused by certain types of medications (called immune-checkpoint inhibitors) in patients with genitourinary cancer. Fecal microbiota transplantation may effectively reduce the incidence of immune checkpoint inhibitor-induced diarrhea/colitis.

diarrhea
loperamide
cancer
genitourinary cancer
microbiota
  • 0 views
  • 25 Oct, 2022
  • 1 location
Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients (IPATHER)

This is an open label, single arm, multicenter, phase Ib study to evaluate the safety and clinical activity of the combination of ipatasertib, trastuzumab and pertuzumab in patients with unresectable locally advanced or metastatic HER2-positive breast cancer with tumors harboring PIK3CA mutations, candidates to receive maintenance HP after first line …

her2/neu-positive breast cancer
platelet count
adenocarcinoma
aptt
PIK3CA
  • 5 views
  • 28 Feb, 2022
  • 3 locations
Phase 2a Randomised Double-blind Placebo-controlled Trial to Assess Safety, Efficacy of Artesunate & Curcumin in Crohn's Disease Patients, Who Continue to Have Mild to Moderate Disease Activity on an Adequate Dose of Azathioprine

This is a single center phase 2a, randomised double-blind, placebo-controlled factorial design, proof of concept trial. Patients with Crohn's disease who are on an adequate dose of azathioprine and still continue to active disease (CDAI > 150 and c-reactive protein > 6) will be enrolled. Forty patients will be randomised …

  • 0 views
  • 25 Oct, 2022
  • 1 location