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Found 8 clinical trials
Featured trial
Patients with Heart Failure and currently on a loop diuretic

The purpose of this study is to evaluate the action of the study drug on your kidneys and your ability to eliminate salt and water alongside a diuretic (furosemide). The information gathered during this clinical trial may support further drug development, including larger trials in patients with heart failure.  The study …

furosemide
fatigue
heart failure
  • 96 views
  • 23 Nov, 2020
  • 1 location
Efficacy and Safety of Early Initiation of Canagliflozin in Patients With Acute Decompensated Heart Failure

use of I.V loop diuretic during the hospitalization period.

glomerular filtration rate
  • 0 views
  • 25 Oct, 2022
  • 1 location
Ertugliflozin in Chronic Heart Failure

The purpose of this study is to determine the effects on heart failure signs and symptoms of the use of either ertugliflozin, metolazone or placebo, in conjunction with intravenous loop diuretic

furosemide
edema
chronic heart failure
diuretic therapy
diuretics
  • 0 views
  • 24 May, 2022
  • 1 location
Mechanisms of Diuretic Resistance in Heart Failure (MsDR)

This study will employ a randomized order, double-blind, repeated measures dose ranging design. This design was chosen in order to generate multiple within-subject serial loop diuretic dose

bumetanide
heart failure
  • 0 views
  • 10 Oct, 2022
  • 1 location
Amiloride in Nephrotic Syndrome

The AMILOR study compares treatment of edema in nephrotic syndrome with Amiloride vs. Furosemide.

proteinuria
  • 0 views
  • 20 Oct, 2021
  • 1 location
Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment (DECONGEST)

This is a pragmatic, multicenter, interventional, parallel-arm, randomized, open-label trial to investigate whether a diuretic regimen, based on serial assessment of sodium concentration (UNa) on spot urine samples after diuretic administration and with low-threshold use of combination diuretic therapy, improves decongestion versus usual care in acute heart failure (AHF), potentially …

  • 0 views
  • 03 Jul, 2022
  • 1 location
Protocolized Diuretic Therapy Compared to Standard Care in Emergency Department Patients With Acute Heart Failure

This is a randomized trial of protocolized diuretic therapy guided by urinary sodium compared to structured usual care in ED patients with AHF. Participants will be recruited following an initial standard evaluation in the ED and randomized in a 1:1 fashion to structured usual care or protocolized diuretic therapy guided …

edema
acute heart failure
diuretic therapy
heart failure
  • 0 views
  • 04 Jun, 2022
  • 1 location
Safety & Feasibility of DSR TherApy in Heart FAiluRe pAtients With Persistent Congestion

Feasibility and safety study of the alfapump DSR system in the treatment of volume overloaded heart failure subjects receiving high doses of loop diuretics. Up to 24 subjects will be enrolled in up to 3 centres in Republic of Georgia, and randomized into 2 parallel treatment arms. Once implanted with …

torsemide
furosemide
diuretics
nt-probnp
anesthesia
  • 0 views
  • 09 Jun, 2021
  • 2 locations