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Found 44 clinical trials
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Advanced Breast Cancer with Visceral Metastases

People with advanced breast cancer are asked to participate in a research study being conducted by White Plains Hospital.  

advanced breast cancer
  • 22 views
  • 02 Aug, 2019
  • 1 location
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

progesterone
HER2
doxorubicin
tubal ligation
residual tumor
  • 17 views
  • 24 Jan, 2021
  • 51 locations
Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer

This study evaluates whether sequential neo-adjuvant chemotherapy plus surgery followed by Capecitabine could achieve additional benefits over traditional postoperative chemotherapy. In the study group, patients that do not achieve pathological complete response(pCR) will receive sequential neo-adjuvant chemotherapy followed by Capecitabine. In the control group, patients will be treated with postoperative …

renal function
cancer
carcinoma
capecitabine
breast cancer
  • 0 views
  • 21 Jan, 2021
  • 1 location
A Study of LXI-15029 in Patients With Advanced Malignant Solid Tumors

(MTD) of monotherapy. 2.To evaluate the safety and tolerability of LXI-15029 in Chinese postmenopausal patients with metastatic or locally advanced breast cancer with estrogen receptor (+) and human

locally advanced breast cancer
erbb2
exemestane
estrogen receptor
lxi-15029
  • 18 views
  • 26 Jan, 2021
  • 1 location
Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

To explore the feasibility of target biopsy of carbon nanoparticles labelled lymph node after neoadjuvant systemic therapy for cN+ breast cancer, and evaluate whether it can accurately predict axillary lymph node status after neoadjuvant systemic therapy.

  • 0 views
  • 30 Jan, 2021
  • 1 location
Functional Precision Oncology for Metastatic Breast Cancer

This is a pilot study to assess the feasibility of comprehensive genomic characterization and drug screening in metastatic breast cancer. The trial will seek to provide personalized genomic and drug sensitivity information to eligible patients with metastatic breast cancer prior to disease progression on standard treatment. The trial will also …

  • 0 views
  • 14 Apr, 2021
  • 1 location
Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

A pragmatic randomized clinical trial of patients with locally advanced breast cancer randomized to either proton or photon therapy and followed longitudinally for cardiovascular morbidity and

mastectomy
stage iv breast cancer
locally advanced breast cancer
lumpectomy
advanced breast cancer
  • 41 views
  • 27 Jan, 2021
  • 35 locations
Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer

participants with metastatic or locally advanced breast cancer Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective response

breast adenocarcinoma
fulvestrant
ESR1
estrogen receptor
exemestane
  • 213 views
  • 14 Apr, 2021
  • 167 locations
Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer

in patients presenting with locally advanced breast cancer.

axillary lymph node dissection
locally advanced breast cancer
sentinel node
advanced breast cancer
sentinel lymph node biopsy
  • 30 views
  • 24 Jan, 2021
  • 8 locations
Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer

This study evaluates the addition melatonin and metformin to toremifene in the treatment of locally advanced breast cancer. Third of patients will receive toremifene, other third will receive

locally advanced breast cancer
breast cancer staging
advanced breast cancer
  • 1 views
  • 23 Jan, 2021
  • 1 location