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Found 19 clinical trials
Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Although the results obtained from ECOG E5194 cohort 1 (criteria: mammographically detected low- or intermediate-grade DCIS, measuring less than 2.5 cm with margins 3 mm) and RTOG 9804 trial (the same enrolled clinicopathological features to cohort 1 of ECOG E5194 trial) demonstrated that the 7-year ipsilateral breast tumor recurrence (IBTR) …

cancer
mammogram
breast cancer
breast tumor
breast-conserving surgery
  • 9 views
  • 12 Aug, 2019
  • 1 location
[18F]Fluoroestradiol-PET/CT Imaging of Invasive Lobular Carcinoma

FES PET/CT imaging for invasive lobular cancer

  • 0 views
  • 27 Dec, 2020
  • 1 location
Endocrine Response in Women With Invasive Lobular Breast Cancer

inhibitor therapy. In current clinical practice, patients with invasive lobular carcinoma are treated no differently than patients with invasive ductal carcinoma based on the void of information specific to

hormone therapy
anastrozole
ductal carcinoma
aromatase inhibitor
ki-67
  • 83 views
  • 22 Oct, 2020
  • 12 locations
APBI: 27Gy in 5 Fractions for Early Breast Cancer

This study will test the safety of partial breast RT using 27Gy in 5 daily fractions which is expected to be equally tolerated as standard whole breast irradiation (WBI) based on radiobiologic modeling of the fibrosis response of normal tissues but be more convenient and less costly than 3-6 weeks …

sentinel lymph node biopsy
ductal carcinoma
axillary lymph node dissection
breast-conserving surgery
female breast cancer
  • 73 views
  • 08 Nov, 2020
  • 1 location
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

skin carcinoma
beta-human chorionic gonadotropin
human chorionic gonadotropin
carcinoma in situ
carcinoma
  • 335 views
  • 19 Jan, 2021
  • 876 locations
No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography

NAUTILUS study is a prospective, multicenter, RCT. Clinically T1,T2, node negative BCS candidates with no evidence of metastases in AUS are 1:1 randomized into no SLNB group and SLNB group. NAUTILUS study aim to establish the minimally invasive treatment of breast cancer by reexamining the necessity of sentinel lymph node …

breast carcinoma
carcinoma
sentinel node
sentinel lymph node biopsy
invasive breast cancer
  • 0 views
  • 01 Oct, 2020
  • 1 location
ROS1 Targeting With Crizotinib in Advanced E-cadherin Negative ER Positive Lobular Breast Cancer or Diffuse Gastric Cancer Study

The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer tumours. The investigators will also be assessing the side effects of the combination of crizotinib tablets and fulvestrant injections. The side effects and the doses of crizotinib …

measurable disease
ROS1
  • 2 views
  • 04 Jun, 2020
  • 1 location
Intraoperative Imaging of Breast Cancer With Indocyanine Green

According to the World Health Organization, breast cancer is the most common cancer in women, and is responsible for 686,000 new cases every year. The WHO also posit that nearly 420,000 women perished from the disease in 2002. Surgery remains the best option for patients presenting with operable Stage I, …

cancer
sentinel lymph node biopsy
ductal carcinoma
mammogram
breast cancer
  • 6 views
  • 07 Nov, 2020
  • 1 location
Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE)

This trial studies the implementation of decision support tools integrated into the electronic health record and patient portal for patients with atypical hyperplasia or lobular carcinoma in

  • 0 views
  • 15 Jan, 2021
  • 13 locations
Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of treatment and can be completed in one-week (5 working days) and 2) MRI-guided radiotherapy (MRIdian) would limit the volume of normal tissue radiated …

squamous cell carcinoma
cancer
mammogram
breast cancer
partial breast irradiation
  • 1 views
  • 16 Jan, 2021
  • 1 location