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Found 284 clinical trials
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Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

  • 267 views
  • 23 Nov, 2020
  • 5 locations
Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Liver Transplant Recipients With Additional 12-month Follow-up (CONTRAIL I)

The purpose of this study is to investigate the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of two CFZ533 dose regimens in liver transplant recipients.

  • 0 views
  • 24 Mar, 2022
  • 39 locations
Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC) (PiSCATIN)

cholangitis (PSC) for daily intake of 40 mg simvastatin/placebo for 5 years. The aim is to study effect of prognosis of PSC by long term intake of simvastatin. Outcome measures are death, liver

  • 0 views
  • 06 May, 2022
  • 11 locations
Establishment of a Personalized Pharmaceutical Plan in Renal or Hepatic Transplant Patients (GREPH)

The main objective of the study is to evaluate the impact of the Personalized Pharmaceutical Plan on the therapeutic adherence to immunosuppressive treatments one year after liver or kidney transplantation.

  • 0 views
  • 10 Mar, 2022
  • 4 locations
MSC Therapy in Liver Transplantation

The general aim of the present study is to test a cell therapy with third-party allogeneic ex-vivo expanded MSCs as a strategy to induce tolerance in liver transplant recipients. MSCs will be

  • 43 views
  • 22 Jan, 2021
  • 2 locations
Transfusion Strategies for Pediatric Liver Transplantation

The patients assigned to the restrictive group will receive transfusion once the hemoglobin concentration falls below 6.0 g per deciliter, with a target hemoglobin range of 7.5 to 8.0 g per deciliter. Patients assigned to the liberal group will receive transfusion once the hemoglobin concentration falls below 8.0 g per …

  • 4 views
  • 04 Mar, 2022
  • 1 location
Perioperative Analgesia by ESP Catheter on Recipient for Liver Transplantation

surgeries. In Liver transplants different programs has been described top reduce the use of peri-operative opioids but no with the ESP Animal and molecular studies in chronic pain showed the activation of

  • 0 views
  • 17 Apr, 2021
  • 2 locations
Indocyanine Green Clearance Test in Liver Transplantation (LivInG) (LivInG)

The gap between patients awaiting and those undergoing liver transplantation (LT) continues to grow. Marginal organs carry higher risk of failure after LT however they are increasingly used to

  • 0 views
  • 10 Mar, 2022
  • 1 location
Hypotension Prediction Index in Patients Undergoing Liver Transplantation

A prospective, open-label and single-center study to determine whether the use of Acumen Hypotension Prediction Index software predicts the occurrence of hypotension.

  • 0 views
  • 14 May, 2021
  • 1 location
Living Donor Liver Transplantation for CRC Liver Metastases

This study will test the safety and efficacy of living donor liver transplant after standard-of-care chemotherapy for participants with non-resectable liver metastases (LM) from colorectal

Accepts healthy volunteers
  • 0 views
  • 18 May, 2022
  • 1 location