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Found 252 clinical trials
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Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

  • 23 Nov, 2020
  • 5 locations
Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC) (PiSCATIN)

cholangitis (PSC) for daily intake of 40 mg simvastatin/placebo for 5 years. The aim is to study effect of prognosis of PSC by long term intake of simvastatin. Outcome measures are death, liver

  • 06 May, 2022
  • 11 locations
Establishment of a Personalized Pharmaceutical Plan in Renal or Hepatic Transplant Patients (GREPH)

The main objective of the study is to evaluate the impact of the Personalized Pharmaceutical Plan on the therapeutic adherence to immunosuppressive treatments one year after liver or kidney transplantation.

  • 10 Mar, 2022
  • 4 locations
MSC Therapy in Liver Transplantation

The general aim of the present study is to test a cell therapy with third-party allogeneic ex-vivo expanded MSCs as a strategy to induce tolerance in liver transplant recipients. MSCs will be

  • 22 Jan, 2021
  • 2 locations
Hypotension Prediction Index in Patients Undergoing Liver Transplantation

A prospective, open-label and single-center study to determine whether the use of Acumen Hypotension Prediction Index software predicts the occurrence of hypotension.

  • 14 May, 2021
  • 1 location
Indocyanine Green Clearance Test in Liver Transplantation (LivInG) (LivInG)

The gap between patients awaiting and those undergoing liver transplantation (LT) continues to grow. Marginal organs carry higher risk of failure after LT however they are increasingly used to

  • 10 Mar, 2022
  • 1 location
Bioavailability and Practicability of Envarsus Versus Advagraf in Liver Transplant Recipients

Trial participants are randomised within 14 days after liver transplantation surgery in a 1:1 ratio to two alternative treatment arms containing either Envarsus® (test arm) or Advagraf®

  • 30 May, 2022
  • 15 locations
Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients

The hypothesis of this proof-of-concept study is that EPO increases the frequency, stability and/or function of Tregs in liver transplant recipients. We also hypothesize that EPO will have a

  • 02 May, 2022
  • 1 location
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant

liver) work compared to standard immunosuppressive medications after your liver transplant. Also the study will assess how safe the new combination of immunosuppressive medicines are and if there are

  • 04 Oct, 2022
  • 1 location
Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection

tenofovir alafenamide (TAF) has been approved to be highly effective and safe in patients with chronic hepatitis B (CHB), therefore TAF may be a good option in kidney or liver transplant

  • 29 Jun, 2022
  • 1 location