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Found 190 clinical trials
Featured trial
Low-Dose Danazol for the Treatment of Telomere Related Diseases

DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to see …

pulmonary fibrosis
lung disease
anemia
liver disease
hepatic fibrosis
  • 346 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors

A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors

  • 159 views
  • 08 Nov, 2020
  • 1 location
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% (APACHE)

liver failure (ACLF) subjects. The study will involve approximately 40 study centers in the United States, Canada, and Europe with expertise in the management of subjects with ACLF. Subjects

plasma exchange
  • 113 views
  • 02 Mar, 2022
  • 31 locations
Effects of Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites (PRECIOSA)

with ascites (or with prior history of ascites requiring diuretic therapy) with or without acute-on-chronic liver failure (ACLF) at admission or during hospitalization but without ACLF at discharge.

  • 33 views
  • 27 Feb, 2022
  • 29 locations
Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures

Colonoscopy is the most useful exam used to evaluate colorectal diseases, like colorectal polyps and cancer. The appropriate bowel preparation is indispensable for colonoscopy procedures. Polyethylene glycol solution (PEG) is the most frequent laxative medication. However, the taste is poor, and patients need to drink a lot of liquids to …

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2021
  • 1 location
Establishment of a Personalized Pharmaceutical Plan in Renal or Hepatic Transplant Patients (GREPH)

The main objective of the study is to evaluate the impact of the Personalized Pharmaceutical Plan on the therapeutic adherence to immunosuppressive treatments one year after liver or kidney transplantation.

  • 0 views
  • 10 Mar, 2022
  • 4 locations
Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion. Therefore, the aim of the study is to determine whether or not repeated dosing of oral or different method of delivery like intravenous (IV) TXA …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Platelet Transfusion in Acute-on Chronic Liver Failure

Acute on-chronic liver failure (ACLF) is a severe liver disease with a 28-day mortality rate of up to 40%. When the patients get 3 or more organ failures, the 28-day mortality rate is up to 82.6

  • 0 views
  • 26 Jan, 2021
  • 8 locations
Study to Evaluate the Efficacy and Safety of HepaStem in Patients With Acute on Chronic Liver Failure (ACLF) (DHELIVER)

This is an interventional, double blind, randomized (2:1), and placebo-controlled study of 1 dose regimen of HepaStem in patients recently diagnosed (≤1 week) with ACLF grade 1 or 2 on top of Standard of Care (SoC), and for whom the diagnosis is not resolved on the day of infusion.

dose regimen
  • 0 views
  • 23 Mar, 2022
  • 5 locations
Acute Hemodynamic Response to Carvedilol in Predicting Survival in Acute on Chronic Liver Failure Patients - A Pilot Study.

Various parameters will be assessed during the procedure before and after 1 hour of 12.5 mg carvedilol such as HVPG (WHVP - FHVP), SVR, heart rate, cardiac output, cardiac index, Blood pressure (systolic, diastolic and mean), SpO2. Routine treatment of the patients will be continued as per the Institute protocol. …

  • 0 views
  • 26 Mar, 2022
  • 1 location