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Found 8 clinical trials
A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia (STABILIZE-CKD)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC), as adjunct to ACEi/ARB therapy (lisinopril or valsartan), on slowing CKD progression (assessed as the

  • 0 views
  • 05 May, 2022
  • 86 locations
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR)

The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial is a multicenter, prospective, randomized, blinded outcome evaluation (PROBE design) evaluating intensive statin/ACE-I (or ARB)/aspirin treatment (IMT) vs. usual care (UC) in 4,422 symptomatic women patients …

chest pain
atorvastatin
angiography
ischemia
angina pectoris
  • 557 views
  • 26 Feb, 2022
  • 84 locations
Comparison of Optimal Hypertension Regimens (AIMHY-INFORM)

High blood pressure (Hypertension) is extremely common and is a major cause of heart disease, kidney disease and stroke. One in three of the UK (United Kingdom) population will require treatment for hypertension at some point in their lives. A healthy lifestyle alone is often not enough to control blood …

hypertension
combinations
amlodipine
chlorthalidone
lisinopril
  • 601 views
  • 24 Feb, 2022
  • 11 locations
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension

The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water pills, help rid your body of salt and water) will control blood pressure better …

  • 0 views
  • 03 Nov, 2021
  • 1 location
Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

This phase II trial investigates how well lisinopril may work in preventing the progression of non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition where there is an accumulation of

neutrophil count
cancer
  • 0 views
  • 22 Mar, 2022
  • 3 locations
Centrally Acting ACE Inhibition in SLE

, named lisinopril, on resting metabolism in the brain and on cognitive function. The investigators will see if Lisinopril will decrease resting metabolism in the brain and improve cognitive function

sjogren's syndrome
autoimmune disease
18f-fdg
lupus
corticosteroids
  • 0 views
  • 29 Nov, 2021
  • 7 locations
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) (PHRASE)

Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric hypertension and related target organ injury, including in the heart, kidneys, vasculature, and brain. Recruiting children with a new hypertension diagnosis over a …

renin
hypertension
Accepts healthy volunteers
aldosterone
angiotensin
  • 0 views
  • 21 Mar, 2022
  • 1 location
CandeSpartan Study. Candesartan Spanish Response-prediction and Tolerability Study (CandeSpartan)

Observational, prospective, descriptive, open study on response predictors and tolerability of Candesartan in patients >18 years with episodic or chronic migraine with prior failure of three or more preventive drugs. Patients will receive Candesartan the same manner and intensity if they were not enrolled in the study. Vital signs, clinical …

migraine
headache
chronic migraine
headache occurring
headache disorder
  • 2 views
  • 26 Mar, 2022
  • 1 location