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Found 79 clinical trials
Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

This study is being done to help researchers learn more about and successfully diagnose cancer using blood samples and tissue samples from surgeries in patients with suspicious thyroid nodules or thyroid cancer. Diagnosing cancer in this way, as opposed to biopsies, may be less invasive to the patient. Analyzing blood …

  • 0 views
  • 23 Mar, 2022
  • 1 location
LIQUIK: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (LIQUIK)

To explore the non-inferiority of a cfDNA amplicon-based liquid biopsy technology vs. standard of care tissue biopsy-based NGS in detecting guideline- recommended biomarkers in patients with

NTRK
non-squamous non-small cell lung cancer
liquid biopsy
lung carcinoma
EGFR
  • 0 views
  • 30 Jun, 2022
  • 6 locations
Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic Cancer (PROJECTION)

(Group A) or absence of detectable ctDNA (Group B) as determined in a liquid biopsy. After successful surgery of their pancreatic tumor and completion of local histological evaluation, tissue samples

pancreatic neoplasm
resectable pancreatic cancer
cancer chemotherapy
pdac
  • 0 views
  • 25 Apr, 2022
  • 1 location
Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help

carcinosarcoma
  • 0 views
  • 26 Sep, 2021
  • 1 location
Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma (PEP-C)

patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.

carcinoma
tumor markers
clear cell renal cell carcinoma
cancer
nephrectomy
  • 0 views
  • 24 Jul, 2022
  • 1 location
Evaluation of a Novel Microfluidic Device to Purify Metastatic Lung Cancer Patients CTC (Circulating Tumoral Cells)

(spatial heterogeneity) or temporal variations in the molecular makeup of cancer cells (temporal heterogeneity). To overcome these drawbacks, new alternatives are rising up, such as liquid biopsy

liquid biopsy
stage iv non-small cell lung cancer
metastasis
lung carcinoma
  • 0 views
  • 26 Oct, 2021
  • 1 location
Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC) (EXOSARC)

sarcomas has a high potential as a liquid biopsy to evaluate cancer pathogenesis, progression, and treatment efficacy. The purpose of this study is to demonstrate in patients with sarcomas that

advanced soft tissue sarcoma
cancer
metastasis
metastatic sarcoma
anthracyclines
  • 0 views
  • 23 Apr, 2022
  • 3 locations
NGS-based Comprehensive Genomic ctDNA Panel in NSCLC With Immunotherapy

Liquid biopsy based on next-generation sequencing (NGS) method has become an increasingly powerful detection tool for clinical research and practice. As a companion diagnostic panel, circulating

  • 0 views
  • 26 Jan, 2021
  • 1 location
Ovarium Cancer Detection by TEP's and ctDNA

Rationale: Cancer is primarily diagnosed by clinical presentation, imaging and pathological analysis of tissue biopsies, increasingly supported by molecular diagnostics tests. However, late diagnosis and misdiagnosis due to limitations of tissue biopsy acquisition remains a major problem. Therefore, a general blood test to pinpoint cancer early and adequately can be …

cancer of the ovary
tumor markers
tumor cells
  • 15 views
  • 12 Feb, 2022
  • 3 locations
Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies

The purpose of this study is to investigate the feasibility of using ctDNA to support cancer diagnosis and risk stratification where invasive aerosol generating testing (and/or tissue biopsy) is challenging due to infection risk, technical impracticalities and resource limitations, such as during the COVID-19 pandemic and the subsequent recovery period.

bladder tumor
bladder cancer
cancer
lung carcinoma
lung cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location