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Found 119 clinical trials
Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients

To evaluate the predictive value of ctDNA in response, relapse for patients treated with immune checkpoint inhibitors or targeted therapy for ALK, ROS1, MET ex14 skipping.

adenocarcinoma
lung carcinoma
proto-oncogene tyrosine-protein kinase ros
EGFR
targeted therapy
  • 47 views
  • 27 Jan, 2021
  • 1 location
Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated Primary Liver Cancer

To evaluate the predictive value of ctDNA in response, relapse for liver cancer patients treated with immune checkpoint inhibitors

cancer
measurable disease
  • 0 views
  • 29 Jun, 2022
  • 4 locations
Detection of Peritoneal Metastasis of Gastric Cancer by Liquid Biopsy in Peripheral Blood: A Prospective Study

This study is a prospective, multi-omics, observational study aimed at detecting peritoneal metastasis of gastric cancer by combined assays for methylation of cell-free DNA (cfDNA) and other blood-based biomarkers. The study will enroll 384 participants with gastric cancer.

primary cancer
metastasis
  • 0 views
  • 12 May, 2022
Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD

So far, MRD assessment by liquid biopsy (ctDNA) has not been used to predict postoperative treatment efficacy and recurrence risk of GIST patients because of special disease characteristics and

  • 0 views
  • 09 Aug, 2022
  • 1 location
Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

This study is being done to help researchers learn more about and successfully diagnose cancer using blood samples and tissue samples from surgeries in patients with suspicious thyroid nodules or thyroid cancer. Diagnosing cancer in this way, as opposed to biopsies, may be less invasive to the patient. Analyzing blood …

  • 0 views
  • 23 Mar, 2022
  • 1 location
LIQUIK: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (LIQUIK)

To explore the non-inferiority of a cfDNA amplicon-based liquid biopsy technology vs. standard of care tissue biopsy-based NGS in detecting guideline- recommended biomarkers in patients with

NTRK
lung carcinoma
proto-oncogene tyrosine-protein kinase ros
liquid biopsy
cancer chemotherapy
  • 0 views
  • 30 Jun, 2022
  • 6 locations
Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic Cancer (PROJECTION)

(Group A) or absence of detectable ctDNA (Group B) as determined in a liquid biopsy. After successful surgery of their pancreatic tumor and completion of local histological evaluation, tissue samples

pdac
cancer chemotherapy
pancreatic neoplasm
resectable pancreatic cancer
  • 0 views
  • 25 Apr, 2022
  • 1 location
Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help

carcinosarcoma
  • 0 views
  • 26 Sep, 2021
  • 1 location
Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma (PEP-C)

patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.

clear cell renal cell carcinoma
nephrectomy
cancer
carcinoma
tumor markers
  • 0 views
  • 24 Jul, 2022
  • 1 location
Evaluation of a Novel Microfluidic Device to Purify Metastatic Lung Cancer Patients CTC (Circulating Tumoral Cells)

(spatial heterogeneity) or temporal variations in the molecular makeup of cancer cells (temporal heterogeneity). To overcome these drawbacks, new alternatives are rising up, such as liquid biopsy

liquid biopsy
lung carcinoma
stage iv non-small cell lung cancer
metastasis
  • 0 views
  • 26 Oct, 2021
  • 1 location