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Found 119 clinical trials
CAPRI 2 GOIM Study: Investigate the Efficacy and Safety of a Bio-marker Driven Cetuximab-based Treatment Regimen

third line) in a prospective fashion in each patient by liquid biopsy assessment of RAS/BRAF status.

  • 0 views
  • 27 Apr, 2022
  • 8 locations
Omic Technologies to Track Resistance to Palbociclib in Metastatic Breast Cancer

This is a monocentric cohort study, prospective and interventional with minimal risks and constraints for advanced breast cancer. The planned interventions are collection of biological samples at different times. The study will aim to do a descriptive analysis of omics profiles evolution (tumor, volatile organic components) over time, before and …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Liquid Biopsies for the Personalized Management of Patients With Hereditary Diffuse Gastric Cancer

Activating somatic mutations and methylation profiles identified by liquid biopsies could identify CDH1 and CTNNA1 pathogenic variants carriers with invasive diffuse gastric cancer undetectable by upper G-I endoscopy.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Influence of Biopsy Technique on Moleculargenetic Tumor Characterisation in NSCLC (PROFILER)

randomized in a 1:1-setting for bronchoscopic tumor tissue either by forceps or by cryobiopsy. Apart from the bronchoscopic techniques liquid biopsy of peripheral blood and if feasible transbronchial needle

liquid biopsy
lung carcinoma
endobronchial ultrasound
  • 1 views
  • 10 Aug, 2022
  • 1 location
Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced NSCLC Patients (CIRCULAR)

Multicenter prospective cohort study aiming to evaluate the detection rate of EGFR gene mutation in patients with advanced NSCLC in a real-word clinical setting, based on liquid biopsy and

carcinoma
lung carcinoma
EGFR
liquid biopsy
  • 0 views
  • 24 Mar, 2022
  • 1 location
Interest of Broadband Spectroscopy Analysis by Infrared Laser on Liquid Biopsies in Breast Cancer Screening (ICRG0101)

The purpose of this study is to validate the interest of broadband spectroscopy analysis (femto/attosecond by infrared laser) on liquid biopsies in breast cancer screening.

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
  • 5 locations
Analysis of Circulating Tumor Markers in Blood (ALCINA 2)

The circulating tumoral biomarkers in the blood are the object of numerous researches for several decades. The potential clinical interests of these circulating biomarkers are diagnostic, prognostic, predictive of the efficiency of targeted therapies (according to the mutational profile of the cancer), and could allow the study of the mechanisms …

primary cancer
tumor markers
  • 7 views
  • 12 Feb, 2022
  • 2 locations
Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis (CANWATCH)

Adjuvant chemotherapy was unnecessary in pathological stage Ⅱ colorectal cancer following initial treatment of surgery without high risk factors of recurrences. The treatment efficacy of adjuvant chemotherapy for pT1-3N0M0 colorectal cancer following preoperational chemotherapy or chemoradiotherapy remains unclear. Part of clinical local advanced colorectal cancer(cTxN1-2M0), which turn out to be …

cancer
adenocarcinoma
adjuvant chemotherapy
chemotherapy regimen
  • 0 views
  • 21 Mar, 2022
  • 1 location
Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4 (ALCINA4)

Multi-cohort exploratory prospective study. Participation in the ALCINA 4 study does not change the standard management of the patient, including the treatments administered. A sampling schedule will be set up for each cohort. Depending on the clinical context studied and the biomarkers studied and/or sought, the timing of blood samples …

primary cancer
tumor markers
  • 0 views
  • 27 Jun, 2022
  • 1 location
BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Background Accessing brain tumor material for pathological diagnosis requires invasive procedures that carry risk to patients including brain hemorrhages and death. Liquid biopsies are emerging non-invasive alternatives to direct tumour biopsies but the abundance of circulating tumor DNA (ctDNA) is relatively low and this limits our ability to accurately make …

  • 0 views
  • 18 Jul, 2021
  • 1 location