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Found 44 clinical trials
Featured trial
Pemafibrate (K-877) to reduce cardiovascular outcomes by reducing triglycerides in patients with diabetes.

Pemafibrate (K-877) to reduce cardiovascular outcomes by reducing triglycerides in patients with diabetes.

  • 290 views
  • 25 Mar, 2021
  • 1 location
REACH- Reducing Risk With E-based Support for Adherence to Lifestyle Change in Hypertension

2. e-Counseling (vs. Control) will significantly reduce CVD risk, as measured by lipoprotein cholesterol (total, low-density, and total/high-density ratio) and the Framingham 10

stroke
  • 259 views
  • 07 Nov, 2020
  • 3 locations
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts A and B). 56 subjects have been planned for Part A and 76 subjects for Part B

cholesterol level
Accepts healthy volunteers
  • 0 views
  • 13 Jul, 2022
  • 1 location
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients (ACAV)

-density lipoprotein cholesterol (LDL-C) is very common after transplantation with nadir of LDL levels occurring at 6 months. Because of drug-drug interactions, heart transplant recipients cannot be

  • 1 views
  • 10 May, 2022
  • 1 location
Exploring Sex Differences in the Acute Postprandial Metabolic Response to a High-fat Mixed Macronutrient Meal Challenge in Healthy Young Humans (HFM)

Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2 diabetes. Women tend to be better protected against the development of …

Accepts healthy volunteers
  • 0 views
  • 22 Sep, 2022
  • 1 location
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism (HYPOCHOL)

The aim of this study is to identify new targets in cholesterol metabolism thanks to a genetically-based strategy.

  • 0 views
  • 24 Feb, 2022
  • 1 location
Effect of Diet Induced Ketosis on LDL Turnover Rates

There have been concerning case reports of marked elevations of LDL-c in some individuals consuming a KD and Dr. Lewis has been referred a number of these cases to his lipid clinic, some of whom have had extreme elevations of LDL that mimic familial hypercholesterolemia. These marked elevations of LDLc …

Accepts healthy volunteers
  • 22 views
  • 17 Nov, 2021
  • 1 location
Adjuvant Treatment in Elderly Patients With Periodontitis Through the Administration of a Supplement Rich in Oleuropein From the Olive Leaf (OLIVAGING)

Life expectancy has dramatically increased in the last century, although this process has not been always accompanied by an equivalent increase in healthy life expectancy. However, extending longevity without decreasing the risk of age-associated pathologies would not be desirable since non-communicable diseases can diminish seniors' quality of life, raise health-care …

periodontal treatment
chronic periodontitis
  • 0 views
  • 09 Aug, 2022
  • 1 location
Effect of Coffee and Tea Consumption on Adolescent Weight Control

Introduction: The influence of tea or coffee supplementation on body weight in adolescents has never been tested. The aim of the present study was to investigate the effect of tea and coffee consumption on body weight and body fat in an obese adolescent population. Methods: Randomized clinical trial, parallel group …

  • 0 views
  • 25 Mar, 2022
ZOE METHOD Study: Measuring Efficacy THrough Outcomes of Diet

The ZOE Method Study will test the efficacy of personalized nutritional advice, delivered on an individual level through a digital device app; integrating dietary, lifestyle, physiological and metagenomic data, in improving certain cardiometabolic disease risk factors, compared to generalized nutrition advice (control).

Accepts healthy volunteers
  • 0 views
  • 15 Sep, 2022
  • 1 location