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Found 37 clinical trials
Fecal Microbiota Therapy in Steroid Ineligible Alcoholic Hepatitis

Alcoholic hepatitis, the most florid form of alcoholic liver disease, has a very high short-term mortality of up to 50% and no specific therapies are available other than steroids. Steroids also only show a limited utility in improving the short-term survival and boast no evidence of any long-term benefits. Additionally, …

liver disease
  • 0 views
  • 30 Apr, 2022
  • 1 location
A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma

This is a non-randomized, open-label, multi-site phase II therapeutic trial of pembrolizumab and bavituximab in patients with locally advanced HCC. Locally advanced or metastatic HCC is defined as disease that is not amenable to surgical and/or locoregional therapies. Subjects must not have received prior systemic therapy for advanced HCC in …

chemoembolization
hepatitis b surface antigen
hepatitis
measurable disease
systemic therapy
  • 30 views
  • 13 May, 2022
  • 1 location
Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Overweight/Obese Men With T2DM or Prediabetes and Hypogonadism (Test2Func)

The epidemics of obesity, MeTSy, T2DM and CVD are increasing worldwide. Non-alcoholic fatty liver disease (NAFLD) is becoming recognized as a condition possibly involved in the pathogenesis of these diseases. The prevailing hypothesis for NAFLD pathogenesis is the 'two-hit' model, with insulin resistance and hyperinsulinemia playing essential roles, which have …

  • 0 views
  • 02 May, 2022
Safety and Tolerability of Intravenous Fish Oil Lipid Emulsion in Children Undergoing Hematopoietic Cell Transplantation

Children undergoing hematopoietic cell transplantation (HCT) for cancer or blood disorders frequently develop gastrointestinal, metabolic and infectious complications related to preparative high-dose chemotherapy and/or radiation-related toxicity. Parenteral nutrition (PN) with lipid emulsion is commonly required while gastrointestinal complications preclude adequate oral or enteral intake. PN and lipids may increase the …

hla-a
fish oil
myelodysplasia
hematologic disorder
busulfan
  • 8 views
  • 15 Jun, 2022
  • 1 location
A Prospective Study To Identify Predictive Biological Markers In Blood And Cyst Fluid Aspirates From Patients With Pancreatic Cyst Lesions

: clinical progression of disease, cyst size, wall thickening, calcification, communication with pancreatic duct, string sign, cytology, immunohistochemical findings, assay levels of lipase, amylase CEA

  • 0 views
  • 31 May, 2022
  • 1 location
Allosure in Simultaneous Pancreas Kidney Transplant

This study will observe donor derived cell free DNA percentages (via the Allosure test) in combined kidney-pancreas transplant recipients to establish both stable and dysfunctional Allosure assay levels

  • 0 views
  • 01 May, 2022
  • 1 location
Evaluation of Outcomes From Treatment of Benign or Malignant Gastroesophageal Diseases

This study will be a retrospective chart review of patients who have been diagnosed with benign or malignant pancreatic disease under the practice of Dr. Rohan Jeyarajah, M.D., Dr. Houssam Osman M.D., and Dr. Edward Cho M.D., Sc.M. at Methodist Health System Hospital in Richardson, TX. The Investigators plan to …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Lysosomal Acid Lipase (LAL) Deficiency Registry

This is an observational, multi-center, international disease registry designed to collect longitudinal data and create a knowledge base that will be utilized to improve the care and treatment of patients with LAL Deficiency. Participation in the Registry by both physicians and patients is voluntary.

lipase
deficiency
  • 283 views
  • 01 Feb, 2021
  • 28 locations
Causes and Natural History of Dyslipidemias

sharp cookie cutter. Heparin infusion study. Heparin, a blood thinner, releases enzymes that break down fat in the blood. Lipase activity (breakdown of fats) in the blood is measured following

xanthoma
blood test
dyslipidemia
atherosclerosis
cholesterol measurement
  • 47 views
  • 19 Jun, 2022
  • 1 location
Abnormal Lipids - Causes and Effects

At target LDL-C levels, apoB100 concentrations will be higher than recommended levels in the following populations: Tertiary centre lipid clinic patients with raised TG treated with statins. Patients with type 2 diabetes treated with statins. Patients with Chronic Kidney disease (CKD) stages 4 and 5 treated with statins. Despite achieving …

diabetes
statin
cholesterol level
hyperlipidemia
fasting
  • 215 views
  • 14 Jun, 2022
  • 1 location