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Found 38 clinical trials
Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency (PANCAX-3)

The objective of this study is to assess weight stability, functional changes, and quality of life when Pancreaze (pancrelipase) delayed-release 84,000-lipase units (capsules), for main meals

  • 0 views
  • 04 Oct, 2022
  • 1 location
Prevalence and Factors Associated With Pancreatic Enzyme Elevations Among Diabetic Children

enzymes Previous studies indicate that pancreatic enzyme elevations, particularly increased serum lipase levels, are very common in children with DKA. The magnitude of lipase elevation appears to

  • 0 views
  • 02 Jun, 2022
  • 1 location
Timing of Oral Refeeding in Post-ERCP Pancreatitis

for acute pancreatitis is a conservative treatment based on fasting and fluid treatment, and starting oral diet after abdominal pain and pancreatic enzyme levels (amylase/lipase) normalized. However

  • 0 views
  • 21 Oct, 2022
  • 1 location
Prospective Comparison of Surgical Outcomes With Using Integrated Robotic Technology Versus Conventional Laparoscopy for Gastric Cancer Surgery

/lipase levels in serum and drainage fluid will be measured. Invasiveness: value of Single-Site Serum CRP (C reactive protein) levels (day 0, day 3, day 5, and 4 weeks after surgery) and pain

  • 3 views
  • 26 Feb, 2022
  • 1 location
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies

This is a Phase 1 dose-escalation study to evaluate the safety and tolerability of combination treatment of AZD5363 + Olaparib + Durvalumab and to determine the RP2D in patients with advanced or metastatic solid tumor malignancies. The purpose of this trial is to determine if combination treatment of drugs, Olaparib, …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Acute Pancreatitis Targets (APT) Study (APT)

The severity of acute pancreatitis varies considerably from minor symptoms to multi-organ failure. The pathophysiological mechanisms associated with these individual differences in severity are largely unknown. Acute pancreatitis is therefore classified based on clinical characteristics and routine blood samples. Information about pathophysiology and molecular subtypes of acute pancreatitis is needed …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Laxative Properties of Microencapsulated Lipid (Constipation Study)

The present study seeks to build on these observations to assess whether in principle, fat containing microcapsules might help patients experiencing constipation in association with weight loss interventions (including GLP-1 analogues or bariatric surgery) to both avoid/treat constipation and simultaneously optimise their ability to feel full during eating. This potential …

lactulose
Accepts healthy volunteers
chronic constipation
other laxatives
laxative
  • 15 views
  • 13 Jun, 2022
  • 1 location
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism (Glucagon)

Purpose/Objectives: To investigate the effect of hyperglucagonemia on insulin action, particularly on adipose tissue. Research Design/Plan: Normal glucose tolerant subjects will be studied. Study subjects will receive a continuous glucagon infusion for 12 hours. Following glucagon infusion, subjects will receive prime-continuous tracer infusions for additional 4 hours to measure adipocyte …

Accepts healthy volunteers
  • 3 views
  • 07 Oct, 2022
  • 2 locations
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

Epidemiologic, social and economic burdens of type 2 diabetes mellitus (T2DM) keep rising worldwide. Implementation of T2DM preventive trategies is lagging behind. Metabolic surgery, very low calorie diet can induce T2DM remission, but so far for few patients. The investigators will assess the efficacy to cause T2DM remission (primary end …

  • 2 views
  • 23 Aug, 2021
  • 1 location
Antibiotics to Decrease Post ERCP Cholangitis

Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure used to treat bile duct stones, obstructive jaundice, biliary leaks, and a variety of other conditions. There is active debate whether antibiotics should be given prophylactically for ERCP outside of high risk indications including primary sclerosing cholangitis. In part this is due …

  • 10 views
  • 25 Feb, 2022
  • 1 location