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Found 24 clinical trials
Linezolid for Treatment of Nontuberculous Mycobacterial Diseases

A prospective open study to determine the efficacy and tolerability of oral linezolid 600mg./day for the treatment of 40 patients with nontuberculous mycobacterial diseases will be conducted at

  • 0 views
  • 24 Jan, 2021
  • 1 location
Continuous Infusion of Linezolid Versus Intermittent Dosing in the Treatment of Nosocomial Pneumonia

The investigator's goal in this study is to determine the clinical benefit of continuous infusion in comparison with standard intermittent infusion.

x-rays
pneumonia
chest x-ray
linezolid
purulent sputum
  • 0 views
  • 12 Jun, 2021
  • 1 location
Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline Delamanid and Linezolid) With the Current South African Standard of Care

of bedaquiline (BDQ), delamanid (DLM), and linezolid (LNZ), with levofloxacin (LVX) and clofazimine (CFZ) compared to the current South African Standard of Care (Control Strategy) for 9 months for

pulmonary tuberculosis
susceptibility testing
clofazimine
rifampin
linezolid oral tablet
  • 0 views
  • 24 Jan, 2021
  • 1 location
Population Pharmacokinetic-pharmacodynamic (PK-PD) Study of 7 Broad-Spectrum Anti-infective Agents in the Cerebro Spinal Fluid (CSF) of Brain Injured Patients With an External Ventricular Drainage (EVD).

indicated in CNS infections (vancomycin, daptomycin, ceftazidime, meropenem, colistin, linezolid) and to study the Cefepime diffusion in the CSF, known to be highly neurotoxic.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis

This study is a randomized, controlled, multi-center clinical study. The main purpose of this study was to study the efficacy and safety data of total oral short-term therapy as an alternative to injection in the treatment of newly diagnosed RR-TB patients.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis

Antimicrobial treatment could be beneficial in patients with ventilator-associated tracheobronchitis (VAT). The hypothesis of this study is that antibiotic treatment for VAT (3 or 7 days), compared with no antibiotic treatment, would reduce the incidence of transition from VAT to ventilator-associated pneumonia (VAP).

imipenem
pneumonia
tracheobronchitis
invasive mechanical ventilation
antibiotics
  • 0 views
  • 24 Jan, 2021
  • 1 location
Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections

Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species. Systemic bacterial infections due to Staphylococci such as osteomyelitis and septic arthritis, are conditions which require prolonged IV therapy, typically for at least 3-6 weeks, …

vancomycin
prosthetic shoulder
MRSA
staphylococcus aureus
ortho evra
  • 211 views
  • 25 Jan, 2021
  • 1 location
Population Pharmacokinetics of Meropenem and Linezolid in Children With Severe Infectious Diseases

This study is based on the hypothesis that the pharmacokinetics of meropenem and linezolid in severe infectious children are different from mild infectious children and adults. The investigators

  • 0 views
  • 22 Jan, 2021
Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB Tuberculosis

PandrTB is a study of the pharmacokinetics(PK) and pharmacodynamics(PD) of bedaquiline, delamanid, clofazimine, linezolid, moxifloxacin, levofloxacin and pyrazinamide used in novel combinations

clofazimine
moxifloxacin
bedaquiline
delamanid
levofloxacin
  • 0 views
  • 12 May, 2021
  • 4 locations
Drug Monitoring in Critically Ill Patients During Extracorporeal Life Support

observational study using a drug monitoring to derive relevant effects of extracorporeal therapy and clinical patient characteristics for the treatment with meropenem, teicoplanin, linezolid, piperacillin

  • 0 views
  • 23 Jan, 2021
  • 1 location