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Found 13 clinical trials
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BS01 in Patients With Retinitis Pigmentosa

Non-randomized, open label, Phase 1/2 dose escalation study of BS01, a non-replicating, rep/cap-deleted, recombinant adeno-associated virus vector expressing an enhanced light-sensitive

  • 160 views
  • 03 Aug, 2021
  • 1 location
None
Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.

OCT investigators measure thickness of retinal inner and outer nuclear layers. With microperimetry investigators determine light sensitivity in 12 and 4 zones from the fixation point.

cavity
retinal tear
light sensitivity
perfluorodecalin
epiretinal membrane
  • 9 views
  • 08 Nov, 2020
  • 1 location
None
Objectively Diagnose and Monitor Treatment of Light Sensitivity

The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses

photophobia
headache
  • 0 views
  • 08 Jul, 2021
  • 1 location
None
Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer

that has spread to other parts of the body or that has come back. Interstitial photodynamic therapy uses a light-sensitive drug called porfimer sodium. This drug is activated by laser light delivered

  • 1 views
  • 05 Mar, 2021
  • 1 location
None
Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

lymph nodes. Photodynamic therapy consists of injecting a light sensitive drug called a photosensitizer, such as porfimer sodium, into the vein, waiting for it to accumulate in the tumor, and then

lung carcinoma
advanced lung cancer
international normalized ratio
aptt
endobronchial ultrasound
  • 1 views
  • 22 Aug, 2021
  • 1 location
None
visuALL Field Analyzer (vFA) Compared to Standard Automatic Perimetry

To determine age-adjusted reference values of the visuALL Field Analyzer (vFA), to assess the repeatability for each parameter and correlate them with a Standard Automatic Perimetry (SAP) parameters.

brimonidine tartrate ophthalmic solution
optic neuropathy
intraocular pressure
eye disease
neuropathy
  • 2 views
  • 09 Jul, 2021
  • 1 location
None
FIbromyalgia anD GenetIcs Subgroups (FIDGIS)

Fibromyalgia syndrome (FS) is characterized by widespread pain and affect 0.5 to 5 % of the general population, with a higher prevalence in women. Recognized as disease by World Health Organization since 1992, FS concern 1.2 to 2 million of French people and his etiology need to be clarified. This …

  • 5 views
  • 27 Jan, 2021
  • 1 location
None
Duration of Ameluz Application in Acral Actinic Keratoses Response

A phase IV study of a single topical application of ALA for 3 hours or 4 hours to AK on acral sites (hands, feet, arms and legs), and subsequent measurement of clinical efficacy with corresponding PpIX fluorescence imaging.

ameluz
topical application
protoporphyrin ix
  • 4 views
  • 18 Mar, 2021
  • 1 location
None
ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients

Background: despite developments a substantial part of patients with depression will only recover slowly. Light therapy from light boxes has shown antidepressant effects but have several limitations: time consuming, only allowing a fixed spectral distribution, only delivered at a specific time-point, and often with inadequate light intensity delivered at the …

antidepressants
mania
psychosis
depressive episode
drugs of abuse
  • 10 views
  • 22 Jan, 2021
  • 1 location
None
Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

activities like reading and driving. AMD is the leading cause of vision loss in Americans 60 years of age and older. An advanced form of AMD is called geographic atrophy or GA. It happens when light

blindness
atrophy
drusen
geographic atrophy
eye exam
  • 15 views
  • 25 Sep, 2021
  • 1 location