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Found 14 clinical trials
Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus.

The investigators want to study the effect of clobetasol in symptomatic oral lichen planus. The investigators will include 90 patients and randomly alocate them in three groups. The frist group

lichen planus
clobetasol
  • 0 views
  • 26 Jan, 2021
  • 2 locations
A Study to Evaluate the Safety and Effectiveness of Etanercept in Treating Lichen Planus on the Oral Mucosa or Skin

The purpose of this study is to determine the safety and efficacy of etanercept (also known as Enbrel) in the treatment of moderate to severe lichen planus.

  • 21 views
  • 07 Nov, 2020
  • 1 location
Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen Planus

This research study is evaluating the safety and efficacy of Baricitinib in treating Cutaneous Lichen Planus (LP).

  • 0 views
  • 21 Jan, 2022
  • 1 location
TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUN

some cutaneous conditions such as angiofibromas in tuberous sclerosis. Topical applications of sirolimus on the buccal mucosae have been reported in erosive lichen planus and oral pemphigus vulgaris

  • 0 views
  • 11 Mar, 2021
  • 3 locations
Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris

To evaluate the safety and efficacy of ixekizumab in lichen planus and lichen planopilaris clinical response by Total Body Surface (TBS) determination, Investigator Global Assessment (IGA) Score

  • 10 views
  • 10 Sep, 2021
  • 1 location
Laser Therapy in Women With Lichenoid Disorders

Primary aim of the trial is to compare improvement of lichen symptoms according to a composite VAS scale (burning, itching and pain) between women with vulvovaginal laser therapy vs. sham laser therapy at three months.

Accepts healthy volunteers
  • 0 views
  • 16 Jan, 2022
  • 1 location
Dexamethasone Solution and Dexamethasone in Mucolox

Topical steroid therapy is considered the first line of treatment for Oral Inflammatory Ulcerative Diseases with current treatment regimens requiring multiple application or rinses daily. Using Mucolox as a vehicle to deliver topical dexamethasone to the oral mucosa has the potential to effectively prolong contact time between the medication. The …

  • 0 views
  • 29 Jan, 2021
  • 1 location
The AP-GELP Study: A Clinical Trial on the Effects of Apremilast in Female Genital Erosive Lichen Planus

Genital erosive lichen planus (GELP) is a chronic inflammatory disease causing painful genital sores and scarring in women. Treatment options are limited and often unsatisfactory. This trial

apremilast
  • 0 views
  • 29 Aug, 2021
  • 1 location
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases

The molecular mechanisms of action of photo(chemo)therapy in skin diseases are investigated in this study. The phototherapeutic modalities employed include UVB (ultraviolet B), UVA (ultraviolet A), PUVA (psoralen+UVA) and/or extracorporeal photochemotherapy (photopheresis). The study will address whether and how photo(chemo)therapy affects specific biologic pathways in different skin disorders and search …

chemotherapy regimen
extracorporeal photopheresis
psoralen
puva
skin disorder
  • 192 views
  • 21 Jan, 2021
  • 1 location
Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

Background About half the people who have a hematopoietic stem cell transplant using donor cells get cGVHD. This is chronic graft versus host disease. Immune cells from the donor may see the body tissues in the person as foreign and attack, causing damage. The skin is the most commonly affected …

chronic graft versus host disease
neutrophil count
extracorporeal photopheresis
immunosuppressive agents
cancer
  • 32 views
  • 19 Jan, 2022
  • 1 location