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Found 65 clinical trials
Clinical Laboratory Evaluation of Chronic Autonomic Failure

Background The autonomic nervous system controls automatic body functions. Researchers want to improve the tests used to diagnose autonomic failure. Orthostatic hypertension is a drop in blood pressure when a person stands up. Researchers want to focus on this sign of autonomic failure. Objective To improve testing for conditions that …

cardiac symptoms
antidepressant
diabetes
sympathectomies
levodopa
  • 222 views
  • 18 Jun, 2022
  • 1 location
Parkinson's Disease and Movement Disorders Clinical Database

The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and brain images of patients with Parkinson's disease and related disorders receiving care at the Parkinson's disease and Movement Disorders Center and the Hospital of the University of …

depression
dementia
cognitive impairment
  • 0 views
  • 25 Jan, 2022
  • 1 location
Search for Biomarkers of Neurodegenerative Diseases in Idiopathic REM Sleep Behavior Disorder

This study is a prospective study with a mean of 7-year follow-up interval, aims to monitor the progression of -synucleinopathy neurodegeneration by the evolution of prodromal markers and development of clinical disorders in patients with idiopathic REM Sleep Behavior Disorder (iRBD) and healthy controls.

Accepts healthy volunteers
neurodegenerative disorders
synucleinopathy
neurodegeneration
narcolepsy
  • 309 views
  • 14 Feb, 2022
  • 1 location
Gaucherite - A Study to Stratify Gaucher Disease

The purpose of this research is to review data already collected and to collect new data from adults and children in England with Gaucher Disease to determine clinical factors which predict severity and response to therapy of Gaucher disease especially in the areas of bone, cancer and brain conditions.

cancer
enzyme therapy
  • 117 views
  • 28 Jul, 2021
  • 8 locations
Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior Disorder

REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and polysomnographic features of REM sleep without atonia (RSWA), with typical onset age at early 60's. Idiopathic RBD (iRBD) has been suggested as a most specific precursor of α-synucleinopathy-related neurodegeneration (e.g. Parkinson's disease …

constipation
movement disorder
Accepts healthy volunteers
parkinsonism
  • 0 views
  • 03 Jun, 2022
  • 1 location