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Found 65 clinical trials
Neurodegenerative Diseases Registry (NDD Registry)

progressive supranuclear palsy (PSP). Similarly, distinguishing AD from other dementia syndromes including frontotemporal dementia (FTD), dementia with Lewy Bodies (DLB), corticobasal degeneration (CBD) and

Accepts healthy volunteers
brain pathology
alzheimer's disease
drug trials
dementia
  • 129 views
  • 26 Jan, 2022
  • 1 location
Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND)

This is a 5-year observational study recruiting sixteen hundred and fifty individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group of six hundred and fifty aged matched individuals without cognitive deficits. Participants will be recruited at sites across Canada and …

Accepts healthy volunteers
cognitive assessment
cognitive impairment
cognitive disorder
dementia
  • 616 views
  • 23 Feb, 2022
  • 25 locations
A Cross-sectional Study of Sarcopenia in Patients With Parkinson ' s Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease of aging. The average age of PD onset is about 60 years old. Sarcopenia is common in PD patients, and one in five Parkinson's patients is diagnosed with severe sarcopenia. The prevalence of Parkinson's disease is expected to increase in …

  • 0 views
  • 16 Feb, 2021
  • 1 location
The PACE-DLB Study

The PACE-DLB Study is for people with at least moderate dementia with Lewy bodies (DLB) and their primary caregiver. The study's goals are to learn more about the experiences of people with DLB

depression
moderate dementia
hallucinations
dementia
  • 0 views
  • 25 Jan, 2022
  • 5 locations
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease

The study is designed to characterize the clinical, neuropsychological, polysomnographic, and neuroimaging findings among subjects with Alzheimer's disease, Lewy Body dementia, and Parkinsons

mental state examination
dopamine transporter
fdg-pet
dopamine
datscan
  • 12 views
  • 16 Feb, 2022
  • 1 location
Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies.

Lewy Body Dementia (DLB) is the second most common type of neurodegenerative dementia and characterized by loss of cholinergic neurons in the cerebrum and possibly also internal organs. A novel

Accepts healthy volunteers
PET-CT
dopamine
fdg-pet
cognitive impairment
  • 0 views
  • 03 Jun, 2022
  • 1 location
Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia (AD-LBD-EPI)

In the current study, the investigators will examine the extent of subclinical epileptic activity in patients with Alzheimer's disease and patients with Lewy body dementia as compared to healthy

Accepts healthy volunteers
ssri
electroencephalogram
depression
alzheimer's disease
  • 2 views
  • 25 Jan, 2022
  • 2 locations
Synuclein-One Study

The Synuclein-One Study will be evaluating α-synuclein in patients with Parkinson's disease, Multiple System Atrophy, Dementia with Lewy bodies and Pure Autonomic Failure. Using a simple

neurodegenerative disorder
synucleinopathy
parkinson's disease
pure autonomic failure
atrophy
  • 28 views
  • 24 Mar, 2022
  • 22 locations
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

someone has a synucleinopathy such as Parkinson's disease (PD), multiple system atrophy (MSA), or dementia with Lewy bodies(DLB), as opposed to a tauopathy such as progressive supranuclear palsy (PSP) or

Accepts healthy volunteers
synucleinopathy
tauopathies
dementia
parkinsonism
  • 24 views
  • 23 Apr, 2022
  • 2 locations
BEAM: Brain-Eye Amyloid Memory Study (BEAM)

The main objectives for this study are: To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative dementias against standard cognitive assessments and brain imaging measures; and To assess the potential utility of ocular assessments for early detection …

Accepts healthy volunteers
vascular disease
alzheimer's disease
brain imaging
mini-mental state examination
  • 32 views
  • 25 Jan, 2022
  • 5 locations