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Found 65 clinical trials
Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study (ACIST)

The purpose of the study is to evaluate the use of autologous Bone Marrow Derived Stem Cells (BMSC) as a means to improve cognitive impairment as occurs in Alzheimer's Disease and other dementias and to improve behavior and socialization issues which occur in adult Autism Spectrum Disorder. The use of …

alzheimer's disease
cognitive impairment
pervasive developmental disorder
autism
medical therapy
  • 435 views
  • 27 Apr, 2022
  • 3 locations
Inhibition of α-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine

Lewy Body Dementia (LBD), is the second most common form of dementia after Alzheimer's Disease. Dementia is defined as a serious loss in cognitive ability due to damages or disease in the brain

nervous system disorder
dementia
Accepts healthy volunteers
  • 0 views
  • 25 Jan, 2022
  • 1 location
Circulating Ghrelin as a Biomarker for Dementia (GDEM3)

with Lewy bodies (DLB). This study will increase confidence in the replication of our findings. This will be a cross-sectional study using peripheral venous blood.

alzheimer's disease
dementia
Accepts healthy volunteers
  • 0 views
  • 17 Jun, 2022
  • 1 location
Social-Life Enhancing Activities for Caregivers

This study examines a behavioral intervention to improve social connection and reduce loneliness for caregivers of a loved one with Dementia with Lewy Bodies (DLB). The intervention is called

Accepts healthy volunteers
  • 0 views
  • 28 Jun, 2022
  • 1 location
Source Monitoring Déficit in Neuropsychiatric Population

the investigators will measure source-monitoring ability in patients with several neuropsychiatric condition and in healthy controls appaired in age, sex and educational level. Source-monitoring will be measured thanks to internal- and reality-monitoring informatic tasks.The investigators hypothesized patients with fronto-temporal abnormalities would show more marked deficits than patients with only frontal …

dementia
deficit
Accepts healthy volunteers
  • 0 views
  • 05 Apr, 2022
  • 1 location
PET Tau - Neurodegenerative Disease Imaging

The purpose of this study is to measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). Tau has been shown to build up in the brains of patients with injury to brain cells. This study looks at neurodegenerative …

positron emission tomography
cognitive impairment
dementia
ct scan
neurodegenerative disorders
  • 21 views
  • 20 Apr, 2022
  • 1 location
Probiotics in Dementia (PIDE)

Dementia is associated with changes in gut microbiome composition, gut barrier dysfunction, intestinal inflammation and systemic inflammation. Probiotics are a possibility to modulate the gut-brain axis. In this study the effect of probiotics on the gut microbiome and, gut barrier function, inflammation and cognitive dysfunction will be studied.

  • 2 views
  • 16 Mar, 2022
  • 1 location
Validation of Blood Biomarkers for Alzheimer's Disease (ALZAN)

Alzheimer's disease (AD) has gradually become one of the major global public health issues due to its prevalence, which increases with age and life expectancy, and the economic cost of caring for patients whose cognitive decline progressively leads to loss of functional autonomy. The diagnosis of AD is based on …

  • 0 views
  • 27 Jun, 2022
  • 2 locations
Gut Microbiota Across Early Stages of Synucleinopathy: From High-risk Relatives REM Sleep Behavior Disorder to Early Parkinson's Disease

diseases characterized by abnormal aggregation of alpha-synuclein protein in the central nervous system (CNS). Common examples of synucleinopathy are Parkinson's disease (PD) and dementia with Lewy bodies

  • 0 views
  • 05 Jun, 2021
  • 2 locations
PREdictive Risk Factors of Conversion Into Idiopathic RBD. Italian Study (FARPRESTO)

), and Lewy Body Dementia (DLB). In recent years, several follow-up studies on large cohorts of iRBD patients have shown that the idiopathic form evolves towards a symptomatic form in most cases. More

  • 0 views
  • 12 Mar, 2022
  • 1 location