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Found 65 clinical trials
Trial of Parkinson's And Zoledronic Acid (TOPAZ)

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will …

atrophy
lewy body dementia
cognitive assessment
parkinson's disease
parkinsonism
  • 256 views
  • 12 May, 2022
  • 53 locations
18F-DOPA II - PET Imaging Optimization

clinically suspected neuroendocrine tumor. Adult patients (18 or older) with a clinical suspicion of Parkinson's disease or Lewy body dementia. Pediatric (less than 18 years old) or Adult

parkinson's disease
dementia
dopa
  • 8 views
  • 03 May, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

amyloid
psychiatric disorders
parkinson's disease
amyloidosis
dementia
  • 178 views
  • 25 Feb, 2022
  • 1 location
Rural Dementia Caregiver Project

These caregivers are a vulnerable group due to their physical isolation and well-documented rural disparities in health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their ability to maintain their caregiving role. Thus, there is a pressing need for …

Accepts healthy volunteers
alzheimer's disease
depressive symptoms
depression
depressed mood
  • 0 views
  • 26 Jan, 2022
  • 1 location
Telehealth in Lewy Body Dementia

Lewy body dementia (LBD) is the 2nd most common neurodegenerative dementia in the US. Optimal care requires an interdisciplinary approach, however often faced barriers include rural residence

communicative disorders
moderate dementia
dementia
Accepts healthy volunteers
  • 0 views
  • 18 Apr, 2022
  • 1 location
Alpha tACS in Dementia With Lewy Bodies (Alpha-DLB)

, neurodegeneration is accompanied by changes in oscillatory activity leading to the emerging concept of neurological and psychiatric disorders as "oscillopathies". Dementia with Lewy bodies (DLB), which is

neurodegenerative disorder
dementia
  • 0 views
  • 24 Mar, 2022
  • 1 location
K0706 for Patients Diagnosed With Dementia With Lewy Bodies

This study evaluates the safety and tolerability of treatment with K0706 in Dementia with Lewy Bodies (DLB). The hypothesis is that K0706 will be safe and tolerable and that this drug

rigidity
mental disorders
tremor
bradykinesia
rest tremor
  • 267 views
  • 13 Feb, 2022
  • 1 location
Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies

Dementia with Lewy Bodies (DLB) is an alphasynucleinopathy and the second most common form of dementia in the elderly. DLB shares striking neuropathological and clinical similarities with both

rigidity
amn107
mental disorders
tremor
parkinson's disease
  • 4 views
  • 11 May, 2022
  • 1 location
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial (ANeED)

This is a confirmatory investigational medicinal product (IMP) study to investigate the effects on cognition, functional decline and on neuropsychiatric symptoms of the Glucocerebrosidase (GCase) enhancing chaperone ambroxol in participants diagnosed with prodromal and early dementia with Lewybodies (DLB).

mild cognitive impairment
follicle stimulating hormone
mini-mental state examination
dementia
cognitive impairment
  • 0 views
  • 25 Jan, 2022
  • 1 location
Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies (COG1201)

Multi-center, randomized, double-blind, placebo-controlled, 6- month study in subjects with mild to moderate Dementia with Lewy Bodies.

moderate dementia
dementia
  • 0 views
  • 11 May, 2022
  • 1 location