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Found 8 clinical trials
Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients

This is a prospective randomised trial investigating the effect of a preemptive administration of levosimendan on postoperative cardiac NT-proBNP concentrations.

  • 0 views
  • 04 Oct, 2022
  • 1 location
Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS

phase and the risk of failure is high. The mechanism of action of levosimendan, a drug that increases the contractility of the heart, suggests that it would improve the heart-vessel connection and

chronic heart failure
levosimendan
extracorporeal life support
cernevit
  • 0 views
  • 09 May, 2021
  • 1 location
LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients

complications are more frequent with prolonged support and are responsible for significant morbidity and mortality, prolonged ICU and hospital stays and higher costs. Levosimendan, which acts to

  • 0 views
  • 10 Oct, 2021
  • 2 locations
Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation

recommended pharmacotherapy of acute heart failure (diuretics, nitrates, inotropes in patients with signs of low cardiac output - preferentially milrinone or levosimendan). The patients will undergo

  • 0 views
  • 29 Jan, 2021
  • 1 location
Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion: a Randomized Controlled Multi-center Trial (ADAPT)

, low quality of evidence) in patients with persistent tissue hypoperfusion despite adequate fluid resuscitation and vasopressor support. Levosimendan, an alternative inodilator, has failed preventing

hypoperfusion
dobutamine
levosimendan
norepinephrine
ejection fraction
  • 0 views
  • 15 Oct, 2022
  • 15 locations
Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure (COMBAT-SHINE)

The purpose of this trial is to investigate the efficacy and safety of continuous intravenous administration of low dose iloprost versus placebo for 72-hours, in up to a total of 380 patients with septic shock suffering from organ failure. The study hypothesis is that iloprost may be beneficial as an …

organ failure
vasoconstrictor
lactic acid
fluid therapy
sepsis
  • 1 views
  • 16 Feb, 2022
  • 9 locations
Levosimendans Pharmacokinetics in Intensive Care Patients. An Observational Study.

Evaluation of the pharmacokinetics of levosimendan and its metabolites in intensive care patients with normal, reduced and dialysis supported renal function.

dialysis
  • 0 views
  • 22 Oct, 2021
  • 1 location
CCM Italian Registry

The Cardiac Contractility Modulation (CCM) system is a cardiac implantable device indicated for the treatment of patients with symptomatic heart failure with left ventricular systolic dysfunction despite optimal medical and electrical therapy. This system consists of a generator to which two stimulation leads are connected, which are fixed on the …

heart failure
cardiopulmonary exercise testing
chronic heart failure
ejection fraction
heart disease
  • 0 views
  • 03 Mar, 2022
  • 1 location