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Found 21 clinical trials
The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots

This is a randomized controlled trial to assess the effect of a levonorgesterel-releasing intrauterine device (LNG IUD, Mirena®) versus a copper IUD (Paraguard®) on coagulation parameters known to be associated with risk of thrombosis (blood clots). Both the LNG IUD and the copper IUD are FDA approved devices for contraception. …

protein c
thrombin
d-dimer
levonorgestrel
copper
  • 131 views
  • 07 Nov, 2020
  • 1 location
Effects of Cladribine Tablets on the PK of Microgynon

, ethinyl estradiol (EE) and levonorgestrel (LNG).

  • 5 views
  • 02 Sep, 2021
  • 15 locations
Norplant and Irregular Bleeding/Spotting

Irregular or prolonged menstrual bleeding and/or spotting are common side effects in patients using progestin-only hormonal contraception such as levonorgestrel implants (Norplant

antibiotics
doxycycline
gum disease
  • 41 views
  • 07 Nov, 2020
  • 1 location
Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception

This is a randomised controlled trial aimed at comparing the efficacy of levonorgestrel (LNG) co-administered with piroxicam or placebo for oral emergency contraception (EC). Piroxicam is a non

emergency contraception
levonorgestrel
  • 8 views
  • 26 Jan, 2021
  • 2 locations
Levonorgestrel-releasing Intrauterine System and Tubal Ligation

Today tubal sterilization is a simple, safe, and cost-effective method of achieving long-term contraception. Sterilization is an ideal method of permanent contraception in developing countries where access to health care providers is limited. The percentage of women who use sterilization as a method of contraception rises from about 5% between …

  • 0 views
  • 27 Jan, 2021
  • 1 location
A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies

A study to assess the effect of multiple doses of venetoclax on the pharmacokinetics of ethinyl estradiol and levonorgestrel in female participants with different hematological malignancies

hodgkin's disease
lymphoma
cancer
mantle cell lymphoma
  • 6 views
  • 02 Aug, 2021
  • 7 locations
A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception

This is a Phase I multicenter, open-label, dose-ranging, two-dose PK and PD study of injectable LB at administered as a SQ or IM injection at 40 mg and subsequently at 80 mg SQ or IM depending on the pharmacokinetic and pharmacodynamic results obtained at 40 mg.

regular menstrual cycles
levonorgestrel
progesterone
copper
fasting
  • 21 views
  • 31 May, 2021
  • 7 locations
Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer

This randomized phase II trial studies how well levonorgestrel-releasing intrauterine system works when given alone or with everolimus in treating patients with atypical hyperplasia (a pre

hyperplasia
cancer
total bilirubin
atypical hyperplasia
levonorgestrel
  • 85 views
  • 19 Feb, 2021
  • 18 locations
Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

Purpose: This is an open label, single-arm, single-center study of the addition of metformin to standard levonorgestrel-releasing intrauterine device (LR-IUD) treatment of 30 evaluable non

hyperplasia
cancer
adenocarcinoma
progestin
levonorgestrel
  • 195 views
  • 24 Jan, 2021
  • 2 locations
Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine

Open-label randomized controlled trial to study the efficacy of continuous daily use of ethinylestradiol/levonorgestrel (30/150 g/day) compared with vitamin E (400 IU/day) in the treatment of

menstrual migraine
  • 3 views
  • 24 Feb, 2021
  • 1 location