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Found 19 clinical trials
Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception

This is a randomised controlled trial aimed at comparing the efficacy of levonorgestrel (LNG) co-administered with piroxicam or placebo for oral emergency contraception (EC). Piroxicam is a non

Accepts healthy volunteers
emergency contraception
levonorgestrel
  • 14 views
  • 27 May, 2022
  • 1 location
Kuwa Free! - Live Free!

The study investigators are conducting foundational pharmacokinetic (PK) and qualitative studies, among 15-24 years old (inclusive) adolescent girls and young women living with HIV (AGYWLHIV) already on oral antiretroviral therapy (ART) and virally suppressed, leading up to a hybrid type I effectiveness-implementation trial randomizing individual AGYWLHIV to receive long-acting (LA) …

ritonavir
antiretroviral therapy
raltegravir
atazanavir
etonogestrel
  • 0 views
  • 24 Apr, 2022
  • 1 location
Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia

The purpose of this research study is to compare the uterus tissue of women who receive an intrauterine system to treat their endometrial hyperplasia with the uterine tissue of women who receive megestrol acetate to treat their hyperplasia. While both methods are commonly used in practice, investigators would like to …

levonorgestrel
megestrol acetate
dilation and curettage
atypical endometrial hyperplasia
progesterone
  • 0 views
  • 29 May, 2022
  • 1 location
A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies

A study to assess the effect of multiple doses of venetoclax on the pharmacokinetics of ethinyl estradiol and levonorgestrel in female participants with different hematological malignancies

hodgkin's disease
cancer
lymphoma
mantle cell lymphoma
  • 6 views
  • 27 Apr, 2022
  • 3 locations
A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception

This is a Phase I multicenter, open-label, dose-ranging, two-dose PK and PD study of injectable LB at administered as a SQ or IM injection at 40 mg and subsequently at 80 mg SQ or IM depending on the pharmacokinetic and pharmacodynamic results obtained at 40 mg.

regular menstrual cycles
copper
levonorgestrel
Accepts healthy volunteers
fasting
  • 33 views
  • 22 Mar, 2022
  • 7 locations
Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer (LEVER)

This randomized phase II trial studies how well levonorgestrel-releasing intrauterine system works when given alone or with everolimus in treating patients with atypical hyperplasia (a pre

tumor cells
endometrial carcinoma
fasting
everolimus
atypical hyperplasia
  • 97 views
  • 05 Jul, 2022
  • 17 locations
Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

Purpose: This is an open label, single-arm, single-center study of the addition of metformin to standard levonorgestrel-releasing intrauterine device (LR-IUD) treatment of 30 evaluable non

cancer
hyperplasia
adenocarcinoma
endometrial adenocarcinoma
progestin
  • 195 views
  • 14 Sep, 2022
  • 2 locations
Loxenatide Plus LNG-IUS in Endometrial Atypical Hyperplasia

To study if polyethylene glycol loxenatide plus levonorgestrel-releasing intrauterine system (LNG-IUS) will improve response rates in patients with endometrial atypical hyperplasia.

atypical hyperplasia
body mass index
levonorgestrel
  • 0 views
  • 26 Mar, 2022
  • 1 location
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia

To investigate the efficacy of weight management plus levonorgestrel intrauterine system (LNG-IUS) or megestrol acetate (MA) in obese patients with endometrial atypical hyperplasia (EAH) asking

megestrol acetate
mirena
conservative treatment
atypical hyperplasia
body mass index
  • 0 views
  • 08 Jul, 2022
  • 1 location
Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine (WHATT)

Open-label randomized controlled trial to study the efficacy of continuous daily use of ethinylestradiol/levonorgestrel (30/150 µg/day) compared with vitamin E (400 IU/day) in the treatment of

menstrual migraine
  • 3 views
  • 27 Apr, 2022
  • 1 location