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Found 23 clinical trials
Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline Delamanid and Linezolid) With the Current South African Standard of Care

of bedaquiline (BDQ), delamanid (DLM), and linezolid (LNZ), with levofloxacin (LVX) and clofazimine (CFZ) compared to the current South African Standard of Care (Control Strategy) for 9 months for

delamanid
susceptibility testing
levofloxacin
bedaquiline
rifampin
  • 0 views
  • 16 Oct, 2021
  • 1 location
Susceptibility Testing Guided Versus Empirical Therapy for Refractory H. Pylori Infection

test will be used to determine the minimum inhibitory concentrations of levofloxacin, tetracycline, rifabutin, and clarithromycin to guide the selection of antibiotics. Treatment regimens and

  • 0 views
  • 03 Feb, 2021
  • 1 location
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole …

radical cystectomy
trimethoprim
nitrofurantoin
antibiotics
sulfamethoxazole
  • 0 views
  • 10 May, 2022
  • 1 location
Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures

In this study the investigators investigate the feasibility and therapeutic potential of free autologous fat grafting combined to direct visual urethrotomy (DVIU) in the treatment of urethral strictures.

  • 58 views
  • 04 Jun, 2021
  • 1 location
Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection

The prevalence of H. pylori antibiotic resistance has reached an alarming level worldwide. Antibiotic stewardship programs should be urgently developed and implemented. However, H. pylori antimicrobial susceptibility testing (AST) is rarely offered, making local resistance patterns not easily available. Guideline-recommended empiric therapies (GR-ET) may no longer reliably achieve high cure …

  • 0 views
  • 05 Jun, 2022
  • 1 location
Susceptibility Testing of Biofilm to Guide Treatment of Periprosthetic Joint Infections

The overall purpose of this clinical treatment research project is to explore novel diagnostics that can guide the treatment of infections associated to orthopaedic implants, in order to improve patient outcomes and reduce the development of antibiotic resistance. The project aims are: (i) To improve the current diagnostic approaches and …

  • 0 views
  • 29 Aug, 2021
  • 1 location
PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

This phase II trial studies the effect of imipenem-relebactam in treating patients with cancer who have a fever due to low white blood cell counts (febrile neutropenia). In this study, imipenem-relebactam will be compared to the standard-of-care treatment (cefepime, meropenem, or piperacillin/tazobactam) for the treatment of febrile neutropenia. Imipenem-relebactam is …

neutropenia
cell transplantation
cancer
  • 0 views
  • 25 Jul, 2022
  • 1 location
LOAD VS Levofloxacine Concomitant

Comparison Efficacy of two weeks Therapy with Doxycycline,levofloxacine,Tinadizole Versus Levofloxacine,Tinadizole,Amocillin on Eradication of Helicobacter Pylori in Syrian population.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Initial Management of MRONJ Stages I and II a Clinical Trial With Detection of Salivary Biomarkers

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab. It is defined by the presence of exposed bone or a fistula that probes bone in the jaws for a period greater than 8 weeks in patient with a history …

  • 0 views
  • 24 Feb, 2021
  • 1 location
Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB)

Antimicrobial prophylaxis in urological procedures is aimed to reduce the risk of local and systemic postoperative infections such as urinary tract infection or surgical site infection. It should be recommended only when the potential benefit exceeds the anticipated risks and costs. However, a wide variation in the use of periprocedural …

transurethral bladder excision
bladder cancer
urine culture
antimicrobials
antibiotics
  • 9 views
  • 23 Jan, 2021
  • 1 location