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Found 56 clinical trials
Neurodegenerative Diseases Registry (NDD Registry)

With the increase in life expectancy of our population due to advancement of medical diagnosis and treatments, the incidence of age dependent neurodegenerative diseases increased, including Alzheimer's disease (AD), parkinsonian syndromes (PS), small vessel disease (SVD) and motor neuron disease (MND). In spite of the progress of knowing the pathogenesis …

parkinson's disease
parkinsonism
neurodegenerative disorders
corticobasal degeneration
atrophy
  • 129 views
  • 26 Jan, 2022
  • 1 location
Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors (STAT-PD)

In this study, the investigators will examine the association of statin use and dyskinesia in a convenience sample Parkinson's disease patients in the Veterans Administration Health Care System.

levodopa
dyskinesia
  • 40 views
  • 16 May, 2022
  • 2 locations
Social Cognition Dysfunctions in Parkinson's Disease (cognition 2)

of the treatment (levodopa and deep brain stimulation) on the functioning of the NMS

brain stimulation
levodopa
Accepts healthy volunteers
  • 0 views
  • 06 May, 2022
  • 1 location
Motor Network Physiology

for movement. Levodopa medication is also used to modulate this brain networks in patients with PD. The overall objective is to develop a unified theory of basal ganglia thalamocortical (BGTC) circuit

tremor
MRI
brain stimulation
parkinson's disease
bradykinesia
  • 0 views
  • 13 Mar, 2022
  • 1 location
Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease (Steeropt)

The primary objective of the study is to determine if subthalamic nucleus (STN) deep brain stimulation (DBS) using the Vercise directional leads improves neuropsychiatric state and neuropsychiatric fluctuations 12 months after surgery in a large consecutive series of STN-DBS Parkinson's disease (PD) patients.

  • 0 views
  • 25 Jan, 2022
  • 2 locations
Observational Study in Multiple System Atrophy (TALISMAN)

Talisman is global clinical study (20058N) in Multiple System Atrophy (MSA) patients. It will be conducted in two regions (China and the European Union [EU]). There will be common study objectives between China and EU regions (including prospective assessments for MSA disease progression during routine clinical visits for MSA), and …

mri brain
  • 0 views
  • 28 Jul, 2022
  • 2 locations