Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 61 clinical trials
Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Ulcerative Colitis

The project intends to assess the polygenic burden of rare disruptive mutations in Parkinson's disease (PD) and how they influence the phenotype/pathological heterogeneity of disease.

fecal microbiota transplantation
vedolizumab
microbiota
enemas
tumor necrosis factor
  • 0 views
  • 16 Sep, 2021
  • 1 location
TAME-PD - Physical Therapy Atomoxetine and Methylphenidate to Enhance Gait and Balance in Parkinson's Disease

Gait and balance problems are a significant source of disability in patients with Parkinson disease. Physical therapy remains one of the main treatments. On the other hand some medications, such as methyphenidate and atomoxetine, have been tried with promising results. The outcomes in gait and balance in Parkinson disease after …

medication regimen
  • 15 views
  • 19 Feb, 2021
  • 1 location
Enhancement of Stroke Rehabilitation With Levodopa

Trial investigates the benefits and harms of Levodopa /Carbidopa 100/25mg compared to placebo (given in addition to standardized rehabilitation based on the principles of motor learning) and

  • 2 views
  • 24 Feb, 2021
  • 26 locations
A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia

This is a Phase 2b study investigating the efficacy and safety of mesdopetam as adjunct therapy on daily ON-time without troublesome dyskinesia in patients with Parkinson disease. Mesdopetam is taken for 84 days.

levodopa
apomorphine
dyskinesia
  • 0 views
  • 13 Jun, 2021
  • 24 locations
A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia

The current study will explore the efficacy, safety and tolerability of 2 dose combinations of JM-010 to determine the optimal doses of each component to be studied in confirmatory clinical trials.

levodopa
dyskinesia
combinations
parkinson's disease
  • 10 views
  • 17 Sep, 2021
  • 5 locations
A Study of an Investigational Drug to See How it Affects the People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes) Compared to an Approved Drug Used to Treat People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes)

A study of an investigational drug to see how it affects the people with Parkinson's Disease complicated by motor fluctuations ("OFF" Episodes) compared to an approved drug used to treat people with Parkinson's Disease complicated by motor fluctuations ("OFF" Episodes)

  • 215 views
  • 08 Feb, 2021
  • 34 locations
Double Randomized and Placebo Controlled Trail of Tianqi Pingchan Granule to Prevent Levodopa-Induced Dyskinesia

A randomized, double-blind, placebo-controlled multicenter clinical trial was used to observe the effectiveness, safety and side effects of Tianqi Pingzhan Granule in the prevention of levodopa

  • 2 views
  • 23 Jan, 2021
  • 1 location
Effects of PR Oxycodone and of Levodopa vs Placebo on Central Neuropathic Pain in Parkinson's Disease

This study will be conducted in three parallel groups receiving oxycodone, levodopa or placebo, administered as an add-on therapy, in addition to the usual antiparkinsonian treatment. As this

dopamine agonists
levodopa
antidepressants
dopamine
antiparkinsonian agents
  • 18 views
  • 26 Jan, 2021
  • 18 locations
Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease

This trial will assess whether long-acting levodopa taken at night improves obstructive sleep apnea (OSA) in patients with Parkinson's disease (PD), as compared with placebo.

levodopa
sinemet
  • 22 views
  • 06 Sep, 2021
  • 1 location
Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-resistant Freezing of Gait in Parkinson's Disease

The purpose of this research study is to determine if DBS is a safe and effective therapy for severe freezing of gait in patients with Parkinson's Disease. Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of patients with Parkinson's Disease (PD).

movement disorder
dementia
progressive supranuclear palsy
brain stimulation
bradykinesia
  • 0 views
  • 27 Jan, 2021
  • 1 location